Status: Bibliographieeintrag
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| Online-Ressource |
Verfasst von: | Rass, Knuth [VerfasserIn]  |
| Hamsch, Corinna [VerfasserIn]  |
Titel: | Comparable effectiveness of endovenous laser ablation and high ligation with stripping of the great saphenous vein |
Titelzusatz: | two-year results of a randomized clinical trial (RELACS Study) |
Verf.angabe: | Knuth Rass, Norbert Frings, Paul Glowacki, Corinna Hamsch, Stefan Gräber, Thomas Vogt, Wolfgang Tilgen |
Umfang: | 10 S. |
Fussnoten: | First published: 19 September 2011 ; Gesehen am 29.03.2018 |
Titel Quelle: | Enthalten in: Archives of dermatology |
Jahr Quelle: | 2012 |
Band/Heft Quelle: | 148(2012), 1, S. 49-58 |
ISSN Quelle: | 1538-3652 |
Abstract: | Objective To compare the clinical efficacy and safety of endovenous laser treatment (EVLT) with high ligation and stripping (HLS) as standard treatment for great saphenous vein (GSV) insufficiency. Design Two-center randomized controlled trial with 2-year follow-up. Setting Interventions were performed on ambulatory and hospitalized patients at 2 vein centers, a university dermatology department (EVLT-treated group), and a specialized vein clinic (HLS-treated group). Patients Random sample of 400 patients with GSV insufficiency. Interventions Patients were assigned (1:1) to EVLT or HLS of the GSV from September 2004 through March 2007; 185 and 161 patients (limbs), respectively, were treated per protocol. Main Outcome Measures Clinically recurrent varicose veins after surgery (REVAS classification, primary study objective), duplex-detected saphenofemoral recurrence, clinical venous severity scoring (Homburg Varicose Vein Severity Score), hemodynamics (venous refilling time), quality of life (Chronic Venous Insufficiency Questionnaire 2), adverse effects, and visual analog scale -based evaluations of patients' satisfaction. Results Clinically recurrent varicose veins after surgery were similarly observed in both groups: 16.2% (EVLT-treated group) vs 23.1% (HLS-treated group); P = .15. Duplex-detected saphenofemoral refluxes occurred significantly more frequently after EVLT (17.8% vs 1.3%; P < .001). Both treatments equally improved medical condition (Homburg Varicose Vein Severity Score) and disease-related quality of life. Endovenous laser treatment caused more adverse effects (phlebitic reaction, tightness, dyspigmentation) but revealed advantages concerning hemodynamics, recovery, and cosmetic outcome.<h3>Conclusions</h3>Both EVLT and HLS are comparably safe and effective procedures to treat GSV incompetence. The significantly higher rate and the course of duplex-detected saphenofemoral recurrences after EVLT remain a matter of further investigations. Trial Registration isrctn.org Identifier: ISRCTN18322872 |
DOI: | doi:10.1001/archdermatol.2011.272 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Verlag: http://dx.doi.org/10.1001/archdermatol.2011.272 |
| Verlag: https://jamanetwork.com/journals/jamadermatology/fullarticle/1105548 |
| DOI: https://doi.org/10.1001/archdermatol.2011.272 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1571615431 |
Verknüpfungen: | → Zeitschrift |
Comparable effectiveness of endovenous laser ablation and high ligation with stripping of the great saphenous vein / Rass, Knuth [VerfasserIn] (Online-Ressource)
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