Clinical impact of rest dual-energy computed tomography myocardial perfusion in patients with coronary artery disease

• Verfasst von: Baumann, Stefan [VerfasserIn]
• Verfasst von: Becher, Tobias [VerfasserIn]
• Verfasst von: Haubenreisser, Holger [VerfasserIn]
• Verfasst von: Vogler, Nils [VerfasserIn]
• Verfasst von: Borggrefe, Martin [VerfasserIn]
• Verfasst von: Schönberg, Stefan [VerfasserIn]
• Verfasst von: Akın, Ibrahim [VerfasserIn]
• Verfasst von: Henzler, Thomas [VerfasserIn]
• Verfasst von: Loßnitzer, Dirk [VerfasserIn]
• Titel: Clinical impact of rest dual-energy computed tomography myocardial perfusion in patients with coronary artery disease
• Verf.angabe: Stefan Baumann, Marlon Rutsch, Tobias Becher, Philipp Kryeziu, Holger Haubenreisser, Nils Vogler, Celi Anne Schoenike, Martin Borggrefe, Stefan O. Schoenberg, Ibrahim Akin, Thomas Henzler and Dirk Lossnitzer
• E-Jahr: 2017
• Jahr: November-December 2017
• Umfang: 5 S.
• Fussnoten: Gesehen am 04.04.2018
• Titel Quelle: Enthalten in: In vivo
• Ort Quelle: Kapandriti, Attiki : IIAR, 2004
• Jahr Quelle: 2017
• Band/Heft Quelle: 31(2017), 6, Seite 1153-1157
• ISSN Quelle: 1791-7549
• DOI: doi:10.21873/invivo.11182
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: coronary artery disease
• Sach-SW: Coronary CT angiography
• Sach-SW: dual-energy CT
• Sach-SW: myocardial ischemia
• Sach-SW: myocardial perfusion imaging
• K10plus-PPN: 1571680586
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext

Abstract

Background/Aim: To evaluate the hypothesis that patients with suspected coronary artery disease (CAD) assessed using rest dual-energy computed tomography-derived myocardial perfusion imaging (DECT-P), could have fewer invasive coronary angiographies (ICA), showing non-obstructive CAD. Materials and Methods: Patients who had undergone coronary computed tomography angiography (cCTA), rest DECT-P and ICA were analyzed. Results: We evaluated 51 patients (62.7% males, mean age 51.6±12.8 years). Rest DECT-P identified perfusion defects in three (10.7%) of the 28 patients with cCTA negative for luminal stenosis and in 10 (43.5%) of the 23 patients with cCTA positive for luminal stenosis. In total, 21 patients underwent both cCTA and ICA, of which seven (33.3%) showed obstructive CAD. Rest DECT-P revealed false-negative results in four cases (19.1%) and false-positive results in six cases (28.6%). Conclusion: Adding rest DECT-P to cCTA has no incremental diagnostic value over cCTA alone, to exclude haemodynamically significant CAD. Therefore, a rest-stress-DECT-P protocol or a CT-based FFR calculation might be a promising concept to improve diagnostic accuracy in a real clinical setting.