Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling

• Verfasst von: Benke, Kálmán [VerfasserIn]
• Verfasst von: Ruppert, Mihály [VerfasserIn]
• Verfasst von: Radovits, Tamás [VerfasserIn]
• Verfasst von: Szabó, Gábor [VerfasserIn]
• Titel: Heterotopic abdominal rat heart transplantation as a model to investigate volume dependency of myocardial remodeling
• Verf.angabe: Kálmán Benke, Alex Ali Sayour, Csaba Mátyás, Bence Ágg, Balázs Tamás Németh, Attila Oláh, Mihály Ruppert, István Hartyánszky, Zoltán Szabolcs, Tamás Radovits, Béla Merkely, Gábor Szabó
• E-Jahr: 2017
• Jahr: March 2017
• Umfang: 8 S.
• Fussnoten: Gesehen am 11.04.2018
• Titel Quelle: Enthalten in: Transplantation
• Ort Quelle: Hagerstown, Md. : Lippincott Williams & Wilkins, 1963
• Jahr Quelle: 2017
• Band/Heft Quelle: 101(2017), 3, Seite 498-505
• ISSN Quelle: 1534-6080
• DOI: doi:10.1097/TP.0000000000001585
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1571922059

Abstract

<b></b><p>Heterotopic abdominal rat heart transplantation has been extensively used to investigate ischemic-reperfusion injury, immunological consequences during heart transplantations and also to study remodeling of the myocardium due to volume unloading. We provide a unique review on the latter and present a summary of the experimental studies on rat heart transplantation to illustrate changes that occur to the myocardium due to volume unloading. We divided the literature based on whether normal or failing rat heart models were used. This analysis may provide a basis to understand the physiological effects of mechanical circulatory support therapy.</p>