Online-Ressource | |
Verfasst von: | Thiele, Oliver C. [VerfasserIn] |
Seeberger, Robin [VerfasserIn] | |
Flechtenmacher, Christa [VerfasserIn] | |
Hofele, Christof [VerfasserIn] | |
Freier, Kolja [VerfasserIn] | |
Titel: | The role of elective supraomohyoidal neck dissection in the treatment of early, node-negative oral squamous cell carcinoma (OSCC) |
Titelzusatz: | a retrospective analysis of 122 cases |
Verf.angabe: | Oliver C. Thiele, Robin Seeberger, Christa Flechtenmacher, Christof Hofele, Kolja Freier |
E-Jahr: | 2012 |
Jahr: | Jan 2012 |
Umfang: | 4 S. |
Fussnoten: | Gesehen am 18.04.2018 |
Titel Quelle: | Enthalten in: Journal of cranio-maxillofacial surgery |
Ort Quelle: | Oxford [u.a.] : Elsevier, 1987 |
Jahr Quelle: | 2012 |
Band/Heft Quelle: | 40(2012), 1, Seite 67-70 |
ISSN Quelle: | 1878-4119 |
Abstract: | The adequate treatment of the neck in early, clinically node-negative oral squamous cell carcinoma (OSCC) remains controversial. To assess whether elective supraomohyoid neck dissection is reasonable and efficient in early, locally circumscribed OSCC, the outcomes of treatment of 122 patients with an OSCC of clinical UICC stage I or II were retrospectively analysed in this study. Occult lymph node metastases were detected in 13.9% (17/122) of cases. They were more frequently found in 12 compared to T1 tumours (19.7% (14/71) vs. 5.9% (3/51), p = 0.03), age, gender and grading had no influence on the prevalence of occult lymph node metastases (all p-values > 0.05) in a multivariate logistic regression model. Subsequent multivariate survival analysis found that the presence of occult metastases was an independent predictor of reduced disease-free survival after 5 years (82.2% vs. 62.5%, p = 0.004, and 61.9% vs. 17.8%, p < 0.001, respectively). Elective supraomohyoid neck dissection detects occult metastases in early, node-negative OSCC, and patients with early OSCC exhibiting occult metastases should be considered as high risk patients, warranting additional therapeutic regimes. |
DOI: | doi:10.1016/j.jcms.2011.02.001 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Volltext: http://dx.doi.org/10.1016/j.jcms.2011.02.001 |
DOI: https://doi.org/10.1016/j.jcms.2011.02.001 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | biopsy |
cancer | |
cavity | |
floor | |
metastasis | |
mouth | |
n0 neck | |
Occult metastases | |
Oral squamous cell carcinoma | |
predictive factors | |
stage-i | |
Supraomohyoid neck dissection | |
tongue | |
K10plus-PPN: | 1572126302 |
Verknüpfungen: | → Zeitschrift |