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Status: Bibliographieeintrag

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Verfasst von:Algire, Carolyn [VerfasserIn]   i
 Medrikova, Dasa [VerfasserIn]   i
 Herzig, Stephan [VerfasserIn]   i
Titel:White and brown adipose stem cells
Titelzusatz:from signaling to clinical implications
Verf.angabe:Carolyn Algire, Dasa Medrikova, Stephan Herzig
Jahr:2013
Jahr des Originals:2012
Umfang:9 S.
Fussnoten:Published online: 7 October 2012 ; Gesehen am 25.04.2018
Titel Quelle:Enthalten in: Biochimica et biophysica acta
Ort Quelle:Amsterdam [u.a.] : Elsevier, 1947
Jahr Quelle:2013
Band/Heft Quelle:1831(2013), 5, Seite 896-904
ISSN Quelle:1878-2434
Abstract:Epidemiological studies estimate that by the year 2030, 2.16 billion people worldwide will be overweight and 1.12 billion will be obese [1]. Besides its now established function as an endocrine organ, adipose tissue plays a fundamental role as an energy storage compartment. As such, adipose tissue is capable of extensive expansion or retraction depending on the energy balance or disease state of the host, a plasticity that is unparalleled in other organs and - under conditions of excessive energy intake - significantly contributes to the afore mentioned obesity pandemic. Expansion of adipose tissue is driven by both hypertrophy and hyperplasia of adipocytes, which can renew frequently to compensate for cell death. This underlines the importance of adipocyte progenitor cells within the distinct adipose tissue depots to control both energy storage and endocrine functions of adipose tissue. Here we summarize recent findings on the identity and plasticity of adipose stem cells, the involved signaling cascades, and potential clinical implications of these cells for the treatment of metabolic dysfunction in obesity. This article is part of a Special Issue entitled Brown and White Fat: From Signaling to Disease.
DOI:doi:10.1016/j.bbalip.2012.10.001
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1016/j.bbalip.2012.10.001
 DOI: https://doi.org/10.1016/j.bbalip.2012.10.001
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Adipose Tissue, Brown
 Adipose Tissue, White
 Animals
 Humans
 Obesity
 Signal Transduction
 Stem Cells
K10plus-PPN:1572355174
Verknüpfungen:→ Zeitschrift

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