Strategies preventing contrast-induced nephropathy after coronary angiography

• Verfasst von: Ali-Hasan-Al-Saegh, Sadeq [VerfasserIn]
• Verfasst von: Weymann, Alexander [VerfasserIn]
• Titel: Strategies preventing contrast-induced nephropathy after coronary angiography
• Titelzusatz: a comprehensive meta-analysis and systematic review of 125 randomized controlled trials
• Verf.angabe: Sadeq Ali-Hasan-Al-Saegh, Seyed Jalil Mirhosseini, Zahra Ghodratipour, Zahra Sarrafan-Chaharsoughi, Elham Rahimizadeh, Ali Akbar Karimi-Bondarabadi, Fatemeh Haddad, Arezoo Shahidzadeh, Parisa Mahdavi, Ali-Mohammad Dehghan, Mahbube Tahernejad, Azadeh Shahidzadeh, Hamidreza Dehghan, Azam Ghanei, Mohammadreza Lotfaliani, Alexander Weymann, Mohamed Zeriouh, Aron-Frederik Popov, Anton Sabashnikov
• Jahr: 2017
• Umfang: 25 S.
• Fussnoten: Published online: August 1, 2016 ; Gesehen am 25.04.2018
• Titel Quelle: Enthalten in: Angiology
• Ort Quelle: Thousand Oaks, Calif. [u.a.] : Sage, 1950
• Jahr Quelle: 2017
• Band/Heft Quelle: 68(2017), 5, Seite 389-413
• ISSN Quelle: 1940-1574
• DOI: doi:10.1177/0003319716661445
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: adenosine antagonist
• Sach-SW: angiotensin-converting enzyme inhibitors
• Sach-SW: antioxidants
• Sach-SW: contrast-induced nephropathy
• Sach-SW: hydration
• Sach-SW: loop diuretics
• Sach-SW: N-acetylcysteine
• Sach-SW: normal saline
• Sach-SW: sodium bicarbonate
• Sach-SW: statins
• Sach-SW: vitamin C
• K10plus-PPN: 1572364793

Abstract

This systematic review with meta-analysis sought to determine the strength of evidence for the effects of hydration (sodium bicarbonate [SB] and normal saline [NS]), supplementations ( N-acetylcysteine [NAC] and vitamin C), and some common drugs (adenosine antagonists [AAs], statins, loop diuretics, and angiotensin-converting enzyme inhibitors [ACEIs]) on the incidence of contrast-induced nephropathy (CIN) and requirement for hemodialysis after coronary angiography. After screening, a total of 125 trials that reported outcomes were identified. Pooled analysis indicated beneficial effects of SB versus NS (odds ratio [OR] = 0.73; 95% confidence interval [CI]: 0.56-0.94; P = .01), NAC (OR = 0.79; 95% CI: 0.70-0.88; P = .001), vitamin C (OR = 0.64; 95% CI: 0.45-0.89; P = .01), statins (OR = 0.45; 95% CI: 0.35-0.57; P = .001), AA (OR = 0.28; 95% CI: 0.14-0.47; P = .001), loop diuretics (OR = 0.97; 95% CI: 0.33-2.85; P = .9), and ACEI (OR = 1.06; 95% CI: 0.69-1.61; P = .8). Overall, hydration with SB, use of supplements, such as NAC and vitamin C, and administration of statins and AA should always be considered for the prevention of CIN after coronary angiography.