| Online-Ressource |
Verfasst von: | Hoshino, Takao [VerfasserIn]  |
| Hennerici, Michael G. [VerfasserIn]  |
Titel: | Differences in characteristics and outcomes between Asian and non-Asian patients in the TIAregistry.org |
Verf.angabe: | Takao Hoshino, MD; Shinichiro Uchiyama, MD; Lawrence K.S. Wong, MD; Leila Sissani, BS; Gregory W. Albers, MD; Natan M. Bornstein, MD; Louis R. Caplan, MD; Geoffrey A. Donnan, MD; José M. Ferro, MD; Michael G. Hennerici, MD; Julien Labreuche, BS; Philippa C. Lavallée, MD; Carlos Molina, MD; Peter M. Rothwell, MD; Philippe Gabriel Steg, MD; Pierre-Jean Touboul, MD; Éric Vicaut, MD; Pierre Amarenco, MD; on behalf of the TIAregistry.org Investigators |
E-Jahr: | 2017 |
Jahr: | June 5, 2017 |
Umfang: | 9 S. |
Fussnoten: | Gesehen am 28.05.2018 |
Titel Quelle: | Enthalten in: Stroke |
Ort Quelle: | New York, NY : Association, 1970 |
Jahr Quelle: | 2017 |
Band/Heft Quelle: | 48(2017), 7, Seite 1779-1787 |
ISSN Quelle: | 1524-4628 |
Abstract: | Background and Purpose: This study provides the contemporary causes and prognosis of transient ischemic attack (TIA) and minor stroke in Asians and the direct comparisons with non-Asians. Methods: The TIAregistry.org enrolled 4789 patients (1149 Asians and 3640 non-Asians) with a TIA or minor ischemic stroke within 7 days of onset. Every participating facility had systems dedicated to urgent intervention of TIA/stroke patients by specialists. The primary outcome was a composite of cardiovascular death, nonfatal stroke, and nonfatal acute coronary syndrome. Results: Approximately 80% of patients were evaluated within 24 hours of symptom onset. At 1 year, there were no differences in the rates of composite cardiovascular events (6.8% versus 6.0%; P=0.38) and stroke (6.0% versus 4.8%; P=0.11) between Asians and non-Asians. Asians had a lower risk of cerebrovascular disease (stroke or TIA) than non-Asians (adjusted hazard ratio, 0.79; 95% confidence interval, 0.63-0.98; P=0.03); the difference was primarily driven by a lower rate of TIA in Asians (4.2% versus 8.3%; P<0.001). Moderately severe bleeding was more frequent in Asians (0.8% versus 0.3%; P=0.02). In multivariable analysis, multiple acute infarcts (P=0.005) and alcohol consumption (P=0.02) were independent predictors of stroke recurrence in Asians, whereas intracranial stenosis (P<0.001), ABCD2 score (P<0.001), atrial fibrillation (P=0.008), extracranial stenosis (P=0.03), and previous stroke or TIA (P=0.03) were independent predictors in non-Asians. Conclusions: The short-term stroke risk after a TIA or minor stroke was lower than expected when urgent evidence-based care was delivered, irrespective of race/ethnicity or region. However, the predictors of stroke were different for Asians and non-Asians. |
DOI: | doi:10.1161/STROKEAHA.117.016874 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
teilw. kostenfrei: Volltext: http://dx.doi.org/10.1161/STROKEAHA.117.016874 |
| teilw. kostenfrei: Volltext: http://stroke.ahajournals.org.ezproxy.medma.uni-heidelberg.de/content/48/7/1779 |
| DOI: https://doi.org/10.1161/STROKEAHA.117.016874 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | ischemic stroke |
| population |
| prognosis |
| race and ethnicity |
| transient ischemic attack |
K10plus-PPN: | 1575541920 |
Verknüpfungen: | → Zeitschrift |
Differences in characteristics and outcomes between Asian and non-Asian patients in the TIAregistry.org / Hoshino, Takao [VerfasserIn]; June 5, 2017 (Online-Ressource)