| |  Online-Ressource |
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| Verfasst von: | Müller, Cora [VerfasserIn]  |
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| | Waldburger, Nina [VerfasserIn] |
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| | Stampfl, Ulrike [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Schirmacher, Peter [VerfasserIn] |
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| | Sommer, Christof-Matthias [VerfasserIn] |
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| | Longerich, Thomas [VerfasserIn] |
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| Titel: | Non-invasive diagnosis of hepatocellular carcinoma revisited |
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| Verf.angabe: | Cora Mueller, Nina Waldburger, Ulrike Stampfl, Hans-Ulrich Kauczor, Peter Schirmacher, Christof Matthias Sommer, Thomas Longerich |
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| Jahr: | 2018 |
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| Jahr des Originals: | 2017 |
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| Umfang: | 3 S. |
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| Fussnoten: | Published online first: 12 september 2017 ; Gesehen am 06.05.2019 |
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| Titel Quelle: | Enthalten in: Gut |
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| Ort Quelle: | London : BMJ Publishing Group, 1960 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 67(2018), 5, Seite 991-993 |
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| ISSN Quelle: | 1468-3288 |
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| Abstract: | We read with interest the recent work by Ho et al demonstrating mutational hyperactivation of mammalian target of rapamycin signalling in a subgroup of hepatocellular carcinoma (HCC).1 As Berasain and Lechel concluded that the prospect of a positive therapeutic response may outweigh the risk associated with the HCC biopsy procedure2 and histology is essential for confirming a diagnosis of intrahepatic cholangiocarcinoma (ICC),3 we revisited the performance of non-invasive HCC diagnosis as recommended by current guidelines (eg, American Association for the Study of Liver Diseases (AASLD)) in clinical practice. 4 We retrospectively analysed all patients (n=182) in which a CT-guided liver biopsy was performed at a tertiary referral centre within a 9-year period due to the clinical differential diagnosis of HCC. After quality control, a total of 94 biopsies (figure 1A, see online supplementary table 1) could be evaluated. HCC development was associated with the presence of cirrhosis (n=51/65, p<0.001), which was also found in 27% (3/11) of ICC and 33% (1/3) of combined hepatocellular-cholangiocarcinoma (HCC-CC) patients. The number of false-positive non-invasive HCC diagnosis was higher in patients without cirrhosis (n=13/19; table … |
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| DOI: | doi:10.1136/gutjnl-2017-314981 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: http://dx.doi.org/10.1136/gutjnl-2017-314981 |
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| | Volltext: http://gut.bmj.com/content/67/5/991 |
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| | DOI: https://doi.org/10.1136/gutjnl-2017-314981 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | hepatocellular carcinoma |
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| | liver biopsy |
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| | liver imaging |
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| K10plus-PPN: | 1575807610 |
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| Verknüpfungen: | → Zeitschrift |
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Non-invasive diagnosis of hepatocellular carcinoma revisited / Müller, Cora [VerfasserIn]; 2018 (Online-Ressource)
