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Verfasst von:Müller, Jan [VerfasserIn]   i
 Lim, Hyun-ju [VerfasserIn]   i
 Eichinger, Monika [VerfasserIn]   i
 Jobst, Bertram [VerfasserIn]   i
 Eberhardt, Ralf [VerfasserIn]   i
 Gompelmann, Daniela [VerfasserIn]   i
 Puderbach, Michael [VerfasserIn]   i
 Kauczor, Hans-Ulrich [VerfasserIn]   i
 Heußel, Claus Peter [VerfasserIn]   i
 Wielpütz, Mark Oliver [VerfasserIn]   i
Titel:Influence of fissure integrity on quantitative CT and emphysema distribution in emphysema-type COPD using a dedicated COPD software
Verf.angabe:Jan Müller, Hyun-ju Lim, Monika Eichinger, Bertram J. Jobst, Ralf Eberhardt, Daniela Gompelmann, Marcel Koenigkam-Santos, Michael Puderbach, Hans-Ulrich Kauczor, Claus P. Heussel, Mark O. Wielpütz
E-Jahr:2017
Jahr:October 2017
Umfang:7 S.
Fussnoten:Gesehen am 30.05.2018
Titel Quelle:Enthalten in: European journal of radiology
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1990
Jahr Quelle:2017
Band/Heft Quelle:95(2017), Seite 293-299
ISSN Quelle:1872-7727
Abstract:Objectives Fissure integrity (FI) plays a key role in selecting patients for interventional emphysema therapy. We investigated its interference with automated lobar segmentation in quantitative computed tomography (CT) and emphysema distribution. Methods CT was available for 50 patients with chronic obstructive pulmonary disease (COPD). Lobe segmentation was performed fully automated by software and corrected manually. FI was evaluated visually using a %-scale. The influence of FI on emphysema ratio (ER=percentage of lung volume with density values<−950 HU), mean lung density (MLD), emphysema and total volume of adjacent lobes was analyzed. Lobe-based results were compared with respect to FI. Results Differences in ER in adjacent lobes for complete vs. incomplete fissures were 12.4% for the right horizontal, 0.2% and 3% for the right oblique and 4.4% for the left oblique fissure (all p>0.05). Results for emphysema comparing automated vs. manually corrected segmentation exceeded clinically acceptable values, but were not significantly affected by FI (p>0.05). The widest limits of agreement for ER and MLD were noted in the right middle lobe ([−14, 17.4%], [−22.4, 32.4 Hounsfield Units]). Conclusions Automated lobe segmentation and emphysema distribution are not significantly affected by FI. Manual correction of automated lobar segmentation is still recommended in severe emphysema.
DOI:doi:10.1016/j.ejrad.2017.08.015
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1016/j.ejrad.2017.08.015
 Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X17303340
 DOI: https://doi.org/10.1016/j.ejrad.2017.08.015
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Chronic obstructive pulmonary disease
 Collateral ventilation
 Emphysema
 Fissure integrity
 Quantitative computed tomography
K10plus-PPN:1575836629
Verknüpfungen:→ Zeitschrift

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