Improved image quality with simultaneously reduced radiation exposure

• Verfasst von: André, Florian [VerfasserIn]
• Verfasst von: Fortner, Philipp [VerfasserIn]
• Verfasst von: Stiller, Wolfram [VerfasserIn]
• Verfasst von: Buß, Sebastian Johannes [VerfasserIn]
• Verfasst von: Kauczor, Hans-Ulrich [VerfasserIn]
• Verfasst von: Katus, Hugo [VerfasserIn]
• Verfasst von: Korosoglou, Grigorios [VerfasserIn]
• Titel: Improved image quality with simultaneously reduced radiation exposure
• Titelzusatz: Knowledge-based iterative model reconstruction algorithms for coronary CT angiography in a clinical setting
• Verf.angabe: Florian André, Philipp Fortner, Mani Vembar, Dirk Mueller, Wolfram Stiller, Sebastian J. Buss, Hans-Ulrich Kauczor, Hugo A. Katus, Grigorios Korosoglou
• E-Jahr: 2017
• Jahr: 23 February 2017
• Umfang: 8 S.
• Fussnoten: Gesehen am 04.06.2018
• Titel Quelle: Enthalten in: Journal of cardiovascular computed tomography
• Ort Quelle: Amsterdam [u.a.] : Elsevier, 2007
• Jahr Quelle: 2017
• Band/Heft Quelle: 11(2017), 3, Seite 213-220
• ISSN Quelle: 1876-861X
• DOI: doi:10.1016/j.jcct.2017.02.007
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Aged
• Sach-SW: Body Mass Index
• Sach-SW: Computed Tomography Angiography
• Sach-SW: Coronary Angiography
• Sach-SW: Coronary artery disease
• Sach-SW: Coronary CT angiography
• Sach-SW: Coronary Vessels
• Sach-SW: Female
• Sach-SW: Humans
• Sach-SW: Image reconstruction
• Sach-SW: Iterative reconstruction
• Sach-SW: Knowledge Bases
• Sach-SW: Knowledge-based reconstruction
• Sach-SW: Male
• Sach-SW: Middle Aged
• Sach-SW: Multidetector computed tomography
• Sach-SW: Radiation Dosage
• Sach-SW: Radiation exposure
• Sach-SW: Radiographic Image Interpretation, Computer-Assisted
• Sach-SW: Signal-To-Noise Ratio
• K10plus-PPN: 1575941414

Abstract

BACKGROUND: The aim of this study was to assess the potential for radiation dose reduction using knowledge-based iterative model reconstruction (K-IMR) algorithms in combination with ultra-low dose body mass index (BMI)-adapted protocols in coronary CT angiography (coronary CTA). METHODS: Forty patients undergoing clinically indicated coronary CTA were randomly assigned to two groups with BMI-adapted (I: <25.0 kg/m2, II: <28.0 kg/m2, III: <30.0 kg/m2, IV: ≥30.0 kg/m2) low dose (LD, I: 100kVp/75 mAs, II: 100kVp/100 mAs, III: 100kVp/150 mAs, IV: 120kVp/150 mAs, n = 20) or ultra-low dose (ULD, I: 100kVp/50 mAs, II: 100kVp/75 mAs, III: 100kVp/100 mAs, IV: 120kVp/100 mAs, n = 20) protocols. Prospectively-triggered coronary CTA was performed using a 256-MDCT with the lowest reasonable scan length. Images were generated with filtered back projection (FBP), a noise-reducing hybrid iterative algorithm (iD, levels 2/5) and K-IMR using cardiac routine (CR) and cardiac sharp settings, levels 1-3. RESULTS: Groups were comparable regarding anthropometric parameters, heart rate, and scan length. The use of ULD protocols resulted in a significant reduction of radiation exposure (0.7 (0.6-0.9) mSv vs. 1.1 (0.9-1.7) mSv; p < 0.02). Image quality was significantly better in the ULD group using K-IMR CR 1 compared to FBP, iD 2 and iD 5 in the LD group, resulting in fewer non-diagnostic coronary segments (2.4% vs. 11.6%, 9.2% and 6.1%; p < 0.05). CONCLUSIONS: The combination of K-IMR with BMI-adapted ULD protocols results in significant radiation dose savings while simultaneously improving image quality compared to LD protocols with FBP or hybrid iterative algorithms. Therefore, K-IMR allows for coronary CTA examinations with high diagnostic value and very low radiation exposure in clinical routine.