| |  Online-Ressource |
|---|
| Verfasst von: | Herold, Christina [VerfasserIn]  |
|---|
| | Lässer, Marc [VerfasserIn] |
|---|
| | Schmid, Lena A. [VerfasserIn] |
|---|
| | Seidl, Ulrich [VerfasserIn] |
|---|
| | Kong, Li [VerfasserIn] |
|---|
| | Fellhauer, Iven [VerfasserIn] |
|---|
| | Thomann, Philipp [VerfasserIn] |
|---|
| | Schröder, Johannes [VerfasserIn] |
|---|
| Titel: | Hippocampal volume reduction and autobiographical memory deficits in chronic schizophrenia |
|---|
| Verf.angabe: | Christina Josefa Herold, Marc Montgomery Lässer, Lena Anna Schmid, Ulrich Seidl, Li Kong, Iven Fellhauer, Philipp Arthur Thomann, Marco Essig, Johannes Schröder |
|---|
| Jahr: | 2013 |
|---|
| Umfang: | 6 S. |
|---|
| Fussnoten: | Available online 14 November 2012 ; Gesehen am 07.06.2018 |
|---|
| Titel Quelle: | Enthalten in: Psychiatry research |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1979 |
|---|
| Jahr Quelle: | 2013 |
|---|
| Band/Heft Quelle: | 211(2013), 3, Seite 189-194 |
|---|
| ISSN Quelle: | 1872-7123 |
|---|
| Abstract: | Although autobiographical memory (AM) deficits and hippocampal changes are frequently found in schizophrenia, their actual association remained yet to be established. AM performance and hippocampal volume were examined in 33 older, chronic schizophrenic patients and 21 healthy volunteers matched for age, gender and education. Psychopathological symptoms and additional neuropsychological parameters were assessed by using appropriate rating scales; magnetic resonance imaging (MRI) 3-T data were analyzed via an automated region-of-interest procedure. When compared with the control subjects, patients showed significantly decreased left anterior and posterior hippocampal volumes. Episodic but not semantic AM performance was significantly lower in the patients than in the healthy controls. Both episodic and semantic AM deficits were significantly correlated with volume of the left hippocampus in the patient group. In contrast, deficits in verbal memory, working memory and remote semantic memory observed in the patients did not relate to hippocampal volume. Our findings indicate that AM deficits in chronic schizophrenia are associated with hippocampal volume reductions and underline the importance of this pathology in schizophrenia. |
|---|
| DOI: | doi:10.1016/j.pscychresns.2012.04.002 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: http://dx.doi.org/10.1016/j.pscychresns.2012.04.002 |
|---|
| | Volltext: http://www.sciencedirect.com/science/article/pii/S0925492712000637 |
|---|
| | DOI: https://doi.org/10.1016/j.pscychresns.2012.04.002 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | FSL |
|---|
| | Hippocampus |
|---|
| | Magnetic resonance imaging (MRI) |
|---|
| | Medial temporal lobe (MTL) |
|---|
| | Neuropsychology |
|---|
| | Subcortical structures |
|---|
| K10plus-PPN: | 1576155579 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Hippocampal volume reduction and autobiographical memory deficits in chronic schizophrenia / Herold, Christina [VerfasserIn]; 2013 (Online-Ressource)
