Comparison and outcome analysis of patients with takotsubo cardiomyopathy triggered by emotional stress or physical stress

• Verfasst von: Giannakopoulos, Konstantinos [VerfasserIn]
• Verfasst von: El-Battrawy, Ibrahim [VerfasserIn]
• Verfasst von: Schramm, Katja [VerfasserIn]
• Verfasst von: Ansari, Uzair [VerfasserIn]
• Verfasst von: Hoffmann, Ursula [VerfasserIn]
• Verfasst von: Borggrefe, Martin [VerfasserIn]
• Verfasst von: Akın, Ibrahim [VerfasserIn]
• Titel: Comparison and outcome analysis of patients with takotsubo cardiomyopathy triggered by emotional stress or physical stress
• Verf.angabe: Konstantinos Giannakopoulos, Ibrahim El-Battrawy, Katja Schramm, Uzair Ansari, Ursula Hoffmann, Martin Borggrefe and Ibrahim Akin
• E-Jahr: 2017
• Jahr: 27 April 2017
• Umfang: 6 S.
• Fussnoten: Gesehen am 08.06.2018
• Titel Quelle: Enthalten in: Frontiers in psychology
• Ort Quelle: Lausanne : Frontiers Research Foundation, 2010
• Jahr Quelle: 2017
• Band/Heft Quelle: 8(2017) Artikel-Nummer 527, 6 Seiten
• ISSN Quelle: 1664-1078
• DOI: doi:10.3389/fpsyg.2017.00527
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: emotional stress
• Sach-SW: Mortality
• Sach-SW: Physical stress
• Sach-SW: prognosis
• Sach-SW: Takotsubo Cardiomyopathy
• K10plus-PPN: 1576174921

Abstract

Background: Previous studies revealed that Takotsubo cardiomyopathy (TTC) is triggered by physical and emotional stresses. This study was performed to determine the short- and long-term prognostic impact of emotional- and physical stress associated with TTC. Methods and results: Our institutional database constituted a collective of 84 patients diagnosed with TTC between 2003 and 2015. The patients were divided into two groups as per the presence of emotional stress (n=24, 21%) or physical stress (n=60, 52.6%). The endpoint was a composite of in-hospital events (thromboembolic events and life-threatening arrhythmias), myocardial infarction, all-cause of mortality, re-hospitalization due to heart failure, stroke, and recurrence of TTC. A Kaplan-Meier analysis indicated a significantly lower event-free survival rate over a mean follow-up of 5 years in the emotional group than the physical stress group (log-rank, p<0.01). Multivariate Cox regression analysis revealed only emotional stress (HR 0.4, 95% CI: 0.2-0.9, p<0.05) as a negative independent predictor of the primary endpoint. Conclusion: Rates of in-hospital events and short- as well as long-term events were significantly lower in TTC patients suffering from emotional stress as compared to patients with physical stress.