| |  Online-Ressource |
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| Verfasst von: | Giesel, Frederik L. [VerfasserIn]  |
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| | Kratochwil, Clemens [VerfasserIn] |
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| | Wulfert, Sarah [VerfasserIn] |
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| | Zechmann, Christian [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Haberkorn, Uwe [VerfasserIn] |
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| | Ley, Sebastian [VerfasserIn] |
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| Titel: | Comparison of neuroendocrine tumor detection and characterization using DOTATOC-PET in correlation with contrast enhanced CT and delayed contrast enhanced MRI |
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| Verf.angabe: | F.L. Giesel, C. Kratochwil, A. Mehndiratta, S. Wulfert, J.H. Moltz, C.M. Zechmann, H.U. Kauczor, U. Haberkorn, S. Ley |
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| Jahr: | 2012 |
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| Umfang: | 6 S. |
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| Teil: | volume:81 |
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| | year:2012 |
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| | number:10 |
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| | pages:2820-2825 |
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| | extent:6 |
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| Fussnoten: | Available online 9 January 2012 ; Gesehen am 13.06.2018 |
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| Titel Quelle: | Enthalten in: European journal of radiology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1990 |
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| Jahr Quelle: | 2012 |
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| Band/Heft Quelle: | 81(2012), 10, Seite 2820-2825 |
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| ISSN Quelle: | 1872-7727 |
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| Abstract: | Purpose, We evaluated the rate of successful characterization of gastroenteropancreatic neuroendocrine tumors (NETs) present with an increased somatostatin receptor, comparing CE-CT with CE-MRI, each in correlation with DOTATOC-PET. Methods and materials 8 patients with GEP-NET were imaged using CE-MRI (Gd-EOB-DTPA), CE-CT (Imeron 400) and DOTATOC-PET. Contrast-enhancement of normal liver-tissue and metastasis was quantified with ROI-technique. Tumor delineation was assessed with visual-score in blind-read-analysis by two experienced radiologists. Results Out of 40 liver metastases in patients with NETs, all were detected by CE-MRI and the lesion extent could be adequately assessed, whereas CT failed to detect 20% of all metastases. The blind-read-score of CT in arterial and portal phase was median −0.65 and −1.4, respectively, and 2.7 for delayed-MRI. The quantitative ROI-analysis presented an improved contrast-enhancement-ratio with a median of 1.2, 1.6 and 3.3 for CE-CT arterial, portal-phase and delayed-MRI respectively. Conclusion Late CE-MRI was superior to CE-CT in providing additionally morphologic characterization and exact lesion extension of hepatic metastases from neuroendocrine tumor detected with DOTATOC-PET. Therefore, late enhanced Gd-EOB-DTPA-MRI seems to be the adequate imaging modality for combination with DOTATOC-PET to provide complementary (macroscopic and molecular) tumor characterization in hepatic metastasized NETs. |
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| DOI: | doi:10.1016/j.ejrad.2011.11.007 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1016/j.ejrad.2011.11.007 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X11007832 |
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| | DOI: https://doi.org/10.1016/j.ejrad.2011.11.007 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Comparison study |
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| | Contrast enhanced CT |
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| | Contrast enhanced MRI |
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| | Gastroenteropancreatic neuroendocrine tumors |
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| | Gd-EOB-DTPA |
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| | Metastatic liver lesions |
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| | PET-CT |
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| K10plus-PPN: | 1576319539 |
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| Verknüpfungen: | → Zeitschrift |
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Comparison of neuroendocrine tumor detection and characterization using DOTATOC-PET in correlation with contrast enhanced CT and delayed contrast enhanced MRI / Giesel, Frederik L. [VerfasserIn]; 2012 (Online-Ressource)
