Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe

• Verfasst von: Almeida, Jorge [VerfasserIn]
• Verfasst von: Ruttorf, Michaela [VerfasserIn]
• Titel: Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe
• Verf.angabe: Jorge Almeida, Ana R. Martins, Fredrik Bergström, Lénia Amaral, Andreia Freixo, Ana Ganho-Ávila, Stephanie Kristensen, Dongha Lee, Joana Nogueira and Michaela Ruttorf
• Umfang: 6 S.
• Fussnoten: Published online 13 July 2017 ; Gesehen am 18.06.2018
• Titel Quelle: Enthalten in: Cortex
• Jahr Quelle: 2017
• Band/Heft Quelle: 94(2017), S. 176-181
• ISSN Quelle: 1973-8102
• DOI: doi:10.1016/j.cortex.2017.07.001
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1576436128

Abstract

Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned. Here we use excitatory and inhibitory tDCS prior to a functional magnetic resonance imaging (fMRI) experiment to show that neural responses for an area's preferred stimuli depend on the polarity of stimulation. This is an important, yet overlooked, data point in demonstrating the effectiveness of these stimulation techniques. Our results show that response preferences in the target area are dependent on the polarity of the tDCS session preceding the fMRI experiment - these preferences are less distinct in the cathodal than in the anodal session. As such, we show unequivocally that tDCS modulates neural responses. This result is of the utmost importance in demonstrating the effectiveness of tDCS for clinical and experimental purposes.