Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT)

• Verfasst von: Rieken, Stefan [VerfasserIn]
• Verfasst von: Habermehl, Daniel [VerfasserIn]
• Verfasst von: Haberer, Thomas [VerfasserIn]
• Verfasst von: Jäkel, Oliver [VerfasserIn]
• Verfasst von: Debus, Jürgen [VerfasserIn]
• Verfasst von: Combs, Stephanie [VerfasserIn]
• Titel: Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT)
• Titelzusatz: early treatment results and study concepts
• Verf.angabe: Stefan Rieken, Daniel Habermehl, Thomas Haberer, Oliver Jaekel, Jürgen Debus and Stephanie E. Combs
• Fussnoten: Published: 21 March 2012 ; Gesehen am 22.06.2018
• Titel Quelle: Enthalten in: Radiation oncology
• Jahr Quelle: 2012
• Band/Heft Quelle: 7(2012) Artikel-Nummer 41, 7 Seiten
• ISSN Quelle: 1748-717X
• DOI: doi:10.1186/1748-717X-7-41
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1576773965

Abstract

Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion (18 GyE) vs. a proton boost (10 GyE) in addition to photon radiotherapy (50 Gy), the other one investigating reirradiation with escalating total dose schedules starting at 30 GyE. In atypical meningioma patients (WHO °II), a carbon ion boost of 18 GyE is applied to macroscopic tumor residues following previous photon irradiation with 50 Gy.