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Verfasst von:Bickelhaupt, Sebastian [VerfasserIn]   i
 Laun, Frederik B. [VerfasserIn]   i
 Maier-Hein, Klaus H. [VerfasserIn]   i
 Stieber, Anne [VerfasserIn]   i
 Schlemmer, Heinz-Peter [VerfasserIn]   i
Titel:Independent value of image fusion in unenhanced breast MRI using diffusion-weighted and morphological T2-weighted images for lesion characterization in patients with recently detected BI-RADS 4/5 X-ray mammography findings
Verf.angabe:Sebastian Bickelhaupt, Jana Tesdorff, Frederik Bernd Laun, Tristan Anselm Kuder, Wolfgang Lederer, Susanne Teiner, Klaus Maier-Hein, Heidi Daniel, Anne Stieber, Stefan Delorme, Heinz-Peter Schlemmer
Jahr:2017
Jahr des Originals:2016
Umfang:8 S.
Teil:volume:27
 year:2017
 number:2
 pages:562-569
 extent:8
Fussnoten:Gesehen am 22.06.2018 ; Published online: 18 May 2016
Titel Quelle:Enthalten in: European radiology
Ort Quelle:Berlin : Springer, 1991
Jahr Quelle:2017
Band/Heft Quelle:27(2017), 2, Seite 562-569
ISSN Quelle:1432-1084
 1613-3757
Abstract:ObjectivesThe aim of this study was to evaluate the accuracy and applicability of solitarily reading fused image series of T2-weighted and high-b-value diffusion-weighted sequences for lesion characterization as compared to sequential or combined image analysis of these unenhanced sequences and to contrast- enhanced breast MRI.MethodsThis IRB-approved study included 50 female participants with suspicious breast lesions detected in screening X-ray mammograms, all of which provided written informed consent. Prior to biopsy, all women underwent MRI including diffusion-weighted imaging (DWIBS, b = 1500s/mm2). Images were analyzed as follows: prospective image fusion of DWIBS and T2-weighted images (FU), side-by-side analysis of DWIBS and T2-weighted series (CO), combination of the first two methods (CO+FU), and full contrast-enhanced diagnostic protocol (FDP). Diagnostic indices, confidence, and image quality of the protocols were compared by two blinded readers.ResultsReading the CO+FU (accuracy 0.92; NPV 96.1 %; PPV 87.6 %) and the CO series (0.90; 96.1 %; 83.7 %) provided a diagnostic performance similar to the FDP (0.95; 96.1 %; 91.3 %; p > 0.05). FU reading alone significantly reduced the diagnostic accuracy (0.82; 93.3 %; 73.4 %; p = 0.023).ConclusionsMR evaluation of suspicious BI-RADS 4 and 5 lesions detected on mammography by using a non-contrast-enhanced T2-weighted and DWIBS sequence protocol is most accurate if MR images were read using the CO+FU protocol. Key Points • Unenhanced breast MRI with additional DWIBS/T2w-image fusion allows reliable lesion characterization. • Abbreviated reading of fused DWIBS/T2w-images alone decreases diagnostic confidence and accuracy. • Reading fused DWIBS/T2w-images as the sole diagnostic method should be avoided.
DOI:doi:10.1007/s00330-016-4400-9
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: http://dx.doi.org/10.1007/s00330-016-4400-9
 Volltext: https://link.springer.com/article/10.1007/s00330-016-4400-9
 DOI: https://doi.org/10.1007/s00330-016-4400-9
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1576776751
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