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Verfasst von:Ristow, Oliver [VerfasserIn]   i
 Berger, Moritz [VerfasserIn]   i
 Freudlsperger, Christian [VerfasserIn]   i
Titel:Comparison of auto-fluorescence and tetracycline fluorescence for guided bone surgery of medication-related osteonecrosis of the jaw
Titelzusatz:a randomized controlled feasibility study
Verf.angabe:O. Ristow, S. Otto, C. Geiß, V. Kehl, M. Berger, M. Troeltzsch, S. Koerdt, B. Hohlweg-Majert, C. Freudlsperger, C. Pautke
Jahr des Originals:2016
Umfang:10 S.
Fussnoten:Available online14 November 2016 ; Available online 14 November 2016 ; Gesehen am 28.06.2018
Titel Quelle:Enthalten in: International journal of oral and maxillofacial surgery
Jahr Quelle:2017
Band/Heft Quelle:46(2017), 2, S. 157-166
ISSN Quelle:1399-0020
Abstract:Recent studies have indicated that bone shows auto-fluorescence under an appropriate fluorescence lamp. The aim of this preliminary study was to compare the success rates of the established tetracycline fluorescence-guided bone surgery with auto-fluorescence-guided bone surgery in the treatment of medication-related osteonecrosis of the jaw (MRONJ). Forty patients suffering from MRONJ were referred for surgical treatment and were divided randomly into two groups: auto-fluorescence (n=20) or tetracycline fluorescence (n=20) guided bone surgery. The primary endpoint was treatment success, defined as the absence of exposed bone at 8 weeks after surgery. Secondary outcomes assessed were mucosal integrity, signs of infection, pain, and loss of sensitivity; these were evaluated descriptively at 10 days, 8 weeks, 6 months, and 1 year after surgery. At 8 weeks postoperative, 18/20 patients (90%) in the auto-fluorescence group and 17/20 patients (85%) in the tetracycline fluorescence group showed mucosal integrity (P>0.05). At the last follow-up, 94% in the auto-fluorescence group and 89% in the tetracycline fluorescence group presented complete mucosal coverage with no exposed bone, infection, or pain (P>0.05). There was no significant difference between the two techniques for any of the secondary outcomes (P>0.05). The results of this preliminary study show that auto-fluorescence-guided bone surgery has comparable success rates to the established tetracycline fluorescence-guided bone surgery.
DOI:doi:10.1016/j.ijom.2016.10.008
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Verlag: http://dx.doi.org/10.1016/j.ijom.2016.10.008
 Verlag: http://www.sciencedirect.com/science/article/pii/S0901502716302818
 DOI: https://doi.org/10.1016/j.ijom.2016.10.008
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1576934322
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