Peripheral hypoarousal but not preparation-vigilance impairment endures in adhd remission

• Verfasst von: James, Sarah-Naomi [VerfasserIn]
• Verfasst von: Brandeis, Daniel [VerfasserIn]
• Verfasst von: Banaschewski, Tobias [VerfasserIn]
• Titel: Peripheral hypoarousal but not preparation-vigilance impairment endures in adhd remission
• Verf.angabe: Sarah-Naomi James, Celeste H.M. Cheung, Anna-Sophie Rommel, Gráinne McLoughlin, Daniel Brandeis, Tobias Banaschewski, Philip Asherson, and Jonna Kuntsi
• E-Jahr: 2017
• Jahr: March 31, 2017
• Umfang: 8 S.
• Fussnoten: First published March 31, 2017 ; Gesehen am 10.07.2018
• Titel Quelle: Enthalten in: Journal of attention disorders
• Ort Quelle: Thousand Oaks, Calif. : Sage, 1996
• Jahr Quelle: 2017
• Band/Heft Quelle: (2017) Artikel-Nummer 1087054717698813, online first, 8 Seiten
• ISSN Quelle: 1557-1246
• DOI: doi:10.1177/1087054717698813
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1577442385

Abstract

Objective: This study investigates whether impairments associated with persistent ADHD—impaired attention allocation (P3 amplitude), peripheral hypoarousal (skin conductance level [SCL]), and adjustment in preparatory state (contingent negative variation [CNV])—reflect enduring deficits unrelated to ADHD outcome or are markers of ADHD remission. Method: Young people with childhood ADHD (73 persisters and 18 remitters) and 144 controls were compared on neurophysiological measures during two conditions (baseline and fast-incentive) of a four-choice reaction time task. Results: ADHD remitters differed from persisters, and were indistinguishable from controls, on baseline P3 amplitude and fast-incentive CNV amplitude (p ≤ .05). ADHD remitters differed from controls (p ≤ .01), and were indistinguishable from persisters (p > .05), on baseline SCL. Conclusion: Preparation-vigilance measures were markers of ADHD remission, confirming previous findings with other measures. Yet, SCL-measured peripheral hypoarousal emerges as an enduring deficit unrelated to ADHD improvement. Future studies should explore potential compensatory mechanisms that enable efficient preparation-vigilance processes in ADHD remitters.