Infectious complications in patients with myelodysplastic syndromes

• Verfasst von: Radsak, Markus Philipp [VerfasserIn]
• Verfasst von: Hofmann, Wolf-Karsten [VerfasserIn]
• Verfasst von: Nolte, Florian [VerfasserIn]
• Titel: Infectious complications in patients with myelodysplastic syndromes
• Titelzusatz: a review of the literature with emphasis on patients treated with 5-azacitidine
• Verf.angabe: Markus Radsak, Uwe Platzbecker, Cornelia S. Schmidt, Wolf-Karsten Hofmann, Florian Nolte
• E-Jahr: 2017
• Jahr: 21 March 2017
• Umfang: 7 S.
• Fussnoten: Gesehen am 12.07.2018 ; First published: 21 March 2017
• Titel Quelle: Enthalten in: European journal of haematology
• Ort Quelle: Oxford : Wiley-Blackwell, 1987
• Jahr Quelle: 2017
• Band/Heft Quelle: 99(2017), 2, Seite 112-118
• ISSN Quelle: 1600-0609
• DOI: doi:10.1111/ejh.12883
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: 5-azacitidine
• Sach-SW: infection
• Sach-SW: myelodysplastic syndromes
• Sach-SW: socioeconomics and ethics
• Sach-SW: supportive care
• K10plus-PPN: 157754773X

Abstract

Myelodysplastic Syndromes are oligo-clonal stem cell disorders that are associated with cytopenias in the peripheral blood. Major causes for morbidity and mortality in myelodysplastic syndromes (MDS) patients are infections mostly due to bacteria or fungi. Beside leucopenia per se in affected patients, function of white blood cells particularly that of neutrophils seems to be impaired. Here we summarize the available data on infections in MDS patients in general and particularly those treated with 5-azacitidine.