Dose reduction techniques in coronary calcium scoring

• Verfasst von: Vonder, Marleen [VerfasserIn]
• Verfasst von: Meyer, Mathias [VerfasserIn]
• Verfasst von: Henzler, Thomas [VerfasserIn]
• Titel: Dose reduction techniques in coronary calcium scoring
• Titelzusatz: the effect of iterative reconstruction combined with low tube voltage on calcium scores in a thoracic phantom
• Verf.angabe: Marleen Vonder, Gert Jan Pelgrim, Mathias Meyer, Thomas Henzler, Matthijs Oudkerk, Rozemarijn Vliegenthart
• E-Jahr: 2017
• Jahr: 4 June 2017
• Umfang: 7 S.
• Fussnoten: Available online 4 June 2017 ; Gesehen am 16.07.2018
• Titel Quelle: Enthalten in: European journal of radiology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1990
• Jahr Quelle: 2017
• Band/Heft Quelle: 93(2017), Seite 229-235
• ISSN Quelle: 1872-7727
• DOI: doi:10.1016/j.ejrad.2017.06.001
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Coronary artery disease
• Sach-SW: Coronary atherosclerosis
• Sach-SW: Imaging
• Sach-SW: Phantoms
• Sach-SW: Radiation Dosage
• Sach-SW: Tomography
• Sach-SW: X-Ray computed
• K10plus-PPN: 1577646827

Abstract

Objectives: To define a dose-reduced coronary calcium CT protocol that provides similar calcium score values as a conventional 120kVp protocol. Methods: A thorax phantom containing 100 calcifications was scanned with the reference protocol (120kVp, 90 ref mAs, FBP) and 30 dose-reduced protocols (70-110kVp, 90 ref mAs, FBP and iterative reconstruction (IR) levels 1-5) with 3rd generation dual-source CT. For protocols that yielded similar detectability and calcium scores as the reference protocol, additional scans were acquired at reduced ref mAs. Kendall’s τb and independent-samples-median test were used to determine trends and differences in contrast/signal-to-noise ratio (CNR and SNR), dose and calcium scores. Results: The detectability and calcium scores decreased at increasing IR levels (τb<−0.825, p<0.001) and increasing tube voltage (τb<−0.679, p<0.001). For 90kVp-IR3 and 100kVp-IR1, similar detectability and calcium score was found compared to the reference protocol (p>0.206). For these protocols, lower tube currents did not affect the detectability and Agatston score (p>0.206), while CNR and SNR were similar/higher compared to the reference protocol (0.008<p<0.206). Dose reduction was 60.6% (90kVp-IR3) and 43.6% (100kVp-IR1). Conclusions: The protocol of 90kVp-IR3 and 100kVp-IR1 yielded similar calcium detectability, Agatston score and image quality as the reference protocol, with dose reduction up to 60.6%.