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Verfasst von:Köck, Julia [VerfasserIn]   i
 Kromer, Katharina [VerfasserIn]   i
 Siebenlist, Kerstin [VerfasserIn]   i
 Mai, Sabine [VerfasserIn]   i
 Büttner, Sylvia [VerfasserIn]   i
 Fleckenstein, Jens [VerfasserIn]   i
 Wenz, Frederik [VerfasserIn]   i
Titel:Small bowel protection in IMRT for rectal cancer
Titelzusatz:a dosimetric study on supine vs. prone position
Verf.angabe:Julia Koeck, Katharina Kromer, Frank Lohr, Tobias Baack, Kerstin Siebenlist, Sabine Mai, Sylvia Büttner, Jens Fleckenstein, Frederik Wenz
E-Jahr:2017
Jahr:20 February 2017
Umfang:11 S.
Fussnoten:Gesehen am 17.07.2018
Titel Quelle:Enthalten in: Strahlentherapie und Onkologie
Ort Quelle:Berlin : Springer Medizin, 1997
Jahr Quelle:2017
Band/Heft Quelle:193(2017), 7, Seite 578-588
ISSN Quelle:1439-099X
Abstract:Background: This treatment planning study analyzes dose coverage and dose to organs at risk (OAR) in intensity-modulated radiotherapy (IMRT) of rectal cancer and compares prone vs. supine positioning as well as the effect of dose optimization for the small bowel (SB) by additional dose constraints in the inverse planning process. Patients and methods: Based on the CT datasets of ten male patients in both prone and supine position, a total of four different IMRT plans were created for each patient. OAR were defined as the SB, bladder, and femoral heads. In half of the plans, two additional SB cost functions were used in the inverse planning process. Results: There was a statistically significant dose reduction for the SB in prone position of up to 41% in the high and intermediate dose region, compared with the supine position. Furthermore, the femoral heads showed a significant dose reduction in prone position in the low dose region. Regarding the additional active SB constraints, the dose in the high dose region of the SB was significantly reduced by up to 14% with the additional cost functions. There were no significant differences in the dose distribution of the planning target volume (PTV) and the bladder. Conclusion: Prone positioning can significantly reduce dose to the SB in IMRT for rectal cancer and therefore should not only be used in 3D conformal radiotherapy but also in IMRT of rectal cancer. Further protection of the SB can be achieved by additional dose constraints in inverse planning without jeopardizing the homogeneity of the PTV.
DOI:doi:10.1007/s00066-017-1107-z
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1007/s00066-017-1107-z
 Volltext: https://link.springer.com/article/10.1007/s00066-017-1107-z
 DOI: https://doi.org/10.1007/s00066-017-1107-z
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1577666674
Verknüpfungen:→ Zeitschrift

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