CT-guided bipolar and multipolar radiofrequency ablation (RF ablation) of renal cell carcinoma

• Verfasst von: Sommer, Christof-Matthias [VerfasserIn]
• Verfasst von: Bellemann, Nadine [VerfasserIn]
• Verfasst von: Stampfl, Ulrike [VerfasserIn]
• Verfasst von: Kauczor, Hans-Ulrich [VerfasserIn]
• Verfasst von: Radeleff, Boris [VerfasserIn]
• Titel: CT-guided bipolar and multipolar radiofrequency ablation (RF ablation) of renal cell carcinoma
• Titelzusatz: specific technical aspects and clinical results
• Verf.angabe: C.M. Sommer, G. Lemm, E. Hohenstein, N. Bellemann, U. Stampfl, A.S. Goezen, J. Rassweiler, H.U. Kauczor, B.A. Radeleff, P.L. Pereira
• Jahr: 2013
• Jahr des Originals: 2012
• Umfang: 7 S.
• Fussnoten: First online: 28 August 2012 ; Gesehen am 24.07.2018
• Titel Quelle: Enthalten in: CardioVascular and interventional radiology
• Ort Quelle: Berlin : Springer, 1978
• Jahr Quelle: 2013
• Band/Heft Quelle: 36(2013), 3, Seite 731-737
• ISSN Quelle: 1432-086X
• DOI: doi:10.1007/s00270-012-0468-z
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1577882237

Abstract

Purpose: This study was designed to evaluate the clinical efficacy of CT-guided bipolar and multipolar radiofrequency ablation (RF ablation) of renal cell carcinoma (RCC) and to analyze specific technical aspects between both technologies. Methods: We included 22 consecutive patients (3 women; age 74.2 ± 8.6 years) after 28 CT-guided bipolar or multipolar RF ablations of 28 RCCs (diameter 2.5 ± 0.8 cm). Procedures were performed with a commercially available RF system (Celon AG Olympus, Berlin, Germany). Technical aspects of RF ablation procedures (ablation mode [bipolar or multipolar], number of applicators and ablation cycles, overall ablation time and deployed energy, and technical success rate) were analyzed. Clinical results (local recurrence-free survival and local tumor control rate, renal function [glomerular filtration rate (GFR)]) and complication rates were evaluated. Results: Bipolar RF ablation was performed in 12 procedures and multipolar RF ablation in 16 procedures (2 applicators in 14 procedures and 3 applicators in 2 procedures). One ablation cycle was performed in 15 procedures and two ablation cycles in 13 procedures. Overall ablation time and deployed energy were 35.0 ± 13.6 min and 43.7 ± 17.9 kJ. Technical success rate was 100 %. Major and minor complication rates were 4 and 14 %. At an imaging follow-up of 15.2 ± 8.8 months, local recurrence-free survival was 14.4 ± 8.8 months and local tumor control rate was 93 %. GFR did not deteriorate after RF ablation (50.8 ± 16.6 ml/min/1.73 m2 before RF ablation vs. 47.2 ± 11.9 ml/min/1.73 m2 after RF ablation; not significant). Conclusions: CT-guided bipolar and multipolar RF ablation of RCC has a high rate of clinical success and low complication rates. At short-term follow-up, clinical efficacy is high without deterioration of the renal function.