Chemical basis for alteration of an intraocular lens using a femtosecond laser

• Verfasst von: Bille, Josef F. [VerfasserIn]
• Verfasst von: Engelhardt, Johann [VerfasserIn]
• Verfasst von: Volpp, Hans-Robert [VerfasserIn]
• Verfasst von: Laghouissa, Abdelmoutalib [VerfasserIn]
• Verfasst von: Motzkus, Marcus [VerfasserIn]
• Titel: Chemical basis for alteration of an intraocular lens using a femtosecond laser
• Verf.angabe: Josef F. Bille, Johann Engelhardt, Hans-Robert Volpp, Abdelmoutalib Laghouissa, Marcus Motzkus, Zhongxiang Jiang, and Ruth Sahler
• E-Jahr: 2017
• Jahr: 6 Feb 2017
• Umfang: 15 S.
• Fussnoten: Gesehen am 25.07.2018
• Titel Quelle: Enthalten in: Biomedical optics express
• Ort Quelle: Washington, DC : OSA, 2010
• Jahr Quelle: 2017
• Band/Heft Quelle: 8(2017), 3, Seite 1390-1404
• ISSN Quelle: 2156-7085
• DOI: doi:10.1364/BOE.8.001390
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Femtosecond lasers
• Sach-SW: Laser induced fluorescence
• Sach-SW: Laser sources
• Sach-SW: Negative refractive index
• Sach-SW: Pulsed fiber lasers
• Sach-SW: Refractive index
• K10plus-PPN: 1577935934

Abstract

The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering (CARS) microscopy. Photo-induced hydrolysis of polymeric material in aqueous media produces two hydrophilic functional groups: acid group and alcohol group. The spectral signatures identify two of the hydrophilic polar molecules as N-phenyl-4-(phenylazo)-benzenamine (C18H15N3) and phenazine-1-carboxylic acid (C13H8N2O2). The change in hydrophilicity results in a negative refractive index change in the laser-treated areas.