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Verfasst von:Zhan, Tianzuo [VerfasserIn]   i
 Hahn, Felix [VerfasserIn]   i
 Hielscher, Thomas [VerfasserIn]   i
 Bilge, Asmé [VerfasserIn]   i
 Betge, Johannes [VerfasserIn]   i
 Gaiser, Timo [VerfasserIn]   i
 Kähler, Georg [VerfasserIn]   i
 Ebert, Matthias [VerfasserIn]   i
 Belle, Sebastian [VerfasserIn]   i
Titel:Multiple behavioral factors are associated with occurrence of large, flat colorectal polyps
Verf.angabe:Tianzuo Zhan, Felix Hahn, Thomas Hielscher, Asmé Bilge, Jürgen Grüger, Jürgen Weers, Johannes Betge, Timo Gaiser, Georg Kähler, Matthias P. Ebert, Sebastian Belle
Jahr:2017
Umfang:8 S.
Fussnoten:Published online: 28 November 2016 ; Gesehen am 30.07.2018
Titel Quelle:Enthalten in: International journal of colorectal disease
Ort Quelle:Berlin : Springer, 1986
Jahr Quelle:2017
Band/Heft Quelle:32(2017), 4, Seite 575-582
ISSN Quelle:1432-1262
Abstract:PurposeThe prevalence of advanced dysplasia and synchronous lesions is particularly high in patients with large, flat colorectal polyps. However, the impact of lifestyle on the development of such polyps is poorly investigated. Hence, this study aims to identify associations between behavioral factors and the occurrence of large, flat colorectal polyps.MethodsBehavioral factors were retrospectively analyzed in patients with large, flat polyps and control patients with at most one diminutive polyp. Information on lifestyle factors, comorbidities, and demographic parameters were determined by a structured, self-administered questionnaire.ResultsQuestionnaires of 350 patients with large, flat polyps and 489 control patients were included in the analysis. Most large, flat colorectal polyps contained adenoma with low-grade neoplasia and were located in the right colon. Multivariate analysis showed that advanced age (per 1-year increase—OR 1.09, CI 1.07-1.11, p < 0.0001), frequent cigarette smoking (OR 2.04, CI 1.25-3.32, p = 0.0041), daily consumption of red meat (OR 3.61, CI 1.00-12.96, p = 0.0492), and frequent bowel movements (OR 1.62, CI 1.13-2.33, p = 0.0093) were independent risk factors for occurrence of large, flat colorectal polyps. In contrast, frequent intake of cereals (OR 0.62, CI 0.44-0.88, p = 0.0074) was associated with a reduced risk.ConclusionMultiple behavioral factors modulate the risk for developing large, flat colorectal polyps. This knowledge can be used to improve prevention of colorectal cancer.
DOI:doi:10.1007/s00384-016-2717-0
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1007/s00384-016-2717-0
 Volltext: https://link.springer.com/article/10.1007/s00384-016-2717-0
 DOI: https://doi.org/10.1007/s00384-016-2717-0
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1578054400
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