Time trends in dyspepsia and association with H. pylori and work-related stress

• Verfasst von: Braig, Stefanie [VerfasserIn]
• Verfasst von: Brenner, Hermann [VerfasserIn]
• Titel: Time trends in dyspepsia and association with H. pylori and work-related stress
• Titelzusatz: an observational study in white collar employees in 1996 and 2015
• Verf.angabe: Stefanie Braig, Simon Berger, David Rothenbacher, Stefanie Schmid, Thomas Seufferlein, Hermann Brenner, Dietrich Rothenbacher, Harald Gündel
• E-Jahr: 2018
• Jahr: June 22, 2018
• Umfang: 11 S.
• Teil: volume:13
• Teil: year:2018
• Teil: number:6
• Teil: extent:11
• Fussnoten: Gesehen am 30.07.2018
• Titel Quelle: Enthalten in: PLOS ONE
• Ort Quelle: San Francisco, California, US : PLOS, 2006
• Jahr Quelle: 2018
• Band/Heft Quelle: 13(2018,6) Artikel-Nummer e0199533, 11 Seiten
• ISSN Quelle: 1932-6203
• DOI: doi:10.1371/journal.pone.0199533
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1578067030

Abstract

PURPOSE: We aimed to describe time trends in functional dyspepsia and the association of dyspepsia-related factors, Helicobacter pylori (H. pylori) and work-related stress with functional dyspepsia in white collar employees in 1996 and 2015. MATERIALS AND METHODS: Repeat cross-sectional study conducted in 1996 (n = 190, response rate = 76.1) and 2015 (n = 195, response rate = 40.2) within a health insurance company in South-West Germany. Dyspeptic symptoms measured according to the Rome III criteria, effort-reward imbalance and further work- or dyspepsia-related factors were assessed by self-administered questionnaire. H. pylori infection as possible factor for dyspeptic symptoms was measured by a 13C-urea breath test or an antigen stool test. Kruskal-Wallis tests and multivariable logistic regression models were calculated comparing the upper tertile of dyspeptic symptom scale to the middle and lower tertile. RESULTS: Mean dyspepsia symptom scores and work-related stress did not differ comparing 1996 and 2015. In bivariate analyses, dyspeptic symptom scores were consistently correlated with sex, age, and using antacids. Further dyspepsia-related factors were smoking and non-leading occupational position in 1996 and non-steroidal anti-inflammatory drugs as well as high effort-reward imbalance in 2015. High intrinsic effort was positively associated with high dyspepsia symptom scores in both studies. Following multivariable adjustment, we observed a consistent association between high intrinsic effort at work and dyspeptic symptoms, although the association was only marginally statistically significant in 1996. Furthermore, a strong association of somatization, only measured in 2015, with dyspeptic symptoms was shown. CONCLUSIONS: Dyspepsia-related factors may have changed throughout the last decades. Nevertheless, although occupational situations might differ, the intrinsic effort is still strongly associated with dyspeptic symptoms.