Whole-body MRI in patients with non-bacterial osteitis

• Verfasst von: Arnoldi, Andreas Paul [VerfasserIn]
• Verfasst von: Schlett, Christopher L. [VerfasserIn]
• Verfasst von: Weckbach, Sabine [VerfasserIn]
• Titel: Whole-body MRI in patients with non-bacterial osteitis
• Titelzusatz: radiological findings and correlation with clinical data
• Verf.angabe: A.P. Arnoldi, C.L. Schlett, H. Douis, L.L. Geyer, A.M. Voit, F. Bleisteiner, A.F. Jansson, S. Weckbach
• Jahr: 2017
• Jahr des Originals: 2016
• Umfang: 9 S.
• Fussnoten: First online: 23 September 2016 ; Gesehen am 08.08.2018
• Titel Quelle: Enthalten in: European radiology
• Ort Quelle: Berlin : Springer, 1991
• Jahr Quelle: 2017
• Band/Heft Quelle: 27(2017), 6, Seite 2391-2399
• ISSN Quelle: 1432-1084
• ISSN Quelle: 1613-3757
• DOI: doi:10.1007/s00330-016-4586-x
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Activity score
• Sach-SW: Adolescent
• Sach-SW: Adult
• Sach-SW: Biomarkers
• Sach-SW: Child
• Sach-SW: CRMO
• Sach-SW: Female
• Sach-SW: Humans
• Sach-SW: Magnetic resonance imaging
• Sach-SW: Magnetic Resonance Imaging
• Sach-SW: Male
• Sach-SW: Middle Aged
• Sach-SW: Non-bacterial Osteitis
• Sach-SW: Osteitis
• Sach-SW: Physical Examination
• Sach-SW: Prospective Studies
• Sach-SW: Whole body imaging
• Sach-SW: Whole Body Imaging
• Sach-SW: Young Adult
• K10plus-PPN: 1578361281

Abstract

OBJECTIVES: To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent clinical examination and WB-MRI in which STIR- and T1- weighted images were assessed for NBO-typical lesions. Parameters of interest for RINBO were: number of radiologically active lesions (RAL), size of the patients' maximum RAL presence of extramedullary and spinal involvement. Results were tested for statistical agreement of clinical and MR-based lesion detection. RINBO was tested for correlation with clinical activity. RESULTS: 62/95 clinically/radiologically active lesions were found in 30/33 patients. In 45 % of the cohort, more active lesions were detected by WB-MRI than by clinical examination. RINBO was a significant predictor for the presence of clinically active lesions. CONCLUSION: WB-MRI is a powerful diagnostic tool for patients with NBO which can reveal asymptomatic disease activity. With RINBO a standardized evaluation approach is proposed which helps assessing radiologic disease burden and predicts clinical disease activity. KEY POINTS: • Whole body MRI is a powerful diagnostic tool for patients with non-bacterial Osteitis. • Whole body MRI can reveal asymptomatic disease activity. • The radiologic index RINBO offers a standardized evaluation approach.