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Verfasst von:Artemis, Dimitrios [VerfasserIn]   i
 Wolf, Marc [VerfasserIn]   i
 Blahak, Christian [VerfasserIn]   i
 Szabo, Kristina [VerfasserIn]   i
 Hennerici, Michael G. [VerfasserIn]   i
 Fatar, Marc [VerfasserIn]   i
Titel:Diagnostic and prognostic relevance of magnetic resonance imaging and electrophysiological findings in acute spinal ischemia
Verf.angabe:Dimitrios Artemis, Marc Wolf, Christian Blahak, Kristina Szabo, Michael G. Hennerici, and Marc Fatar
E-Jahr:2017
Jahr:12 January 2017
Umfang:6 S.
Fussnoten:Gesehen am 08.08.2018
Titel Quelle:Enthalten in: Journal of stroke and cerebrovascular diseases
Ort Quelle:New York, NY : Elsevier, 1991
Jahr Quelle:2017
Band/Heft Quelle:26(2017), 3, Seite 459-464
ISSN Quelle:1532-8511
Abstract:OBJECTIVE: Our purpose was to classify the rare entity of spontaneous spinal ischemia with clinical, magnetic resonance-tomographic, and electrophysiological parameters to determine criteria for outcome prediction. METHODS: We analyzed the stroke registry database of the University Hospital Mannheim, Germany, from 2004 to 2010 for patients with a diagnosis of vascular spinal cord ischemia. RESULTS: Ten patients were identified (mean age 65 years [range 50-83], 5 women). In 5 patients an etiology was found. Spinal diffusion-weighted magnetic resonance imaging revealed acute ischemia in 7 patients at initial imaging and this diagnosis was confirmed during the first week in the remaining 3 patients. Electrophysiological studies showed abnormal motor evoked potentials (MEPs) in 8 patients and abnormal somatosensory evoked potentials (SSEPs) in 7 patients. After rehabilitation, 5 patients had regained walking ability, whereas 5 patients stayed wheelchair bound. All patients with unfavorable outcome (American Spinal Injury Association (ASIA) Impairment score [AIS] score of ≤C) showed severe pyramidal tract lesions in MEPs during the first week. All patients with normal MEPs had an excellent outcome (AIS of E, P < .05). CONCLUSIONS: Diffusion-weighted imaging (DWI) is a useful tool to confirm acute spinal ischemia suspected in patients within the first days after symptom onset. Poor outcome was associated with severe electrophysiological abnormalities in MEPs and SSEPs. Normal MEPs were significantly predictive of an excellent prognosis. A multimodal diagnostic approach combining DWI and electrophysiological evaluation facilitates the prediction of the individual clinical outcome.
DOI:doi:10.1016/j.jstrokecerebrovasdis.2016.12.031
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.12.031
 DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.12.031
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Aged
 Aged, 80 and over
 Diffusion Magnetic Resonance Imaging
 diffusion-weighted imaging
 Electromyography
 Evoked Potentials, Motor
 Evoked Potentials, Somatosensory
 Female
 Humans
 magnetic resonance imaging
 Male
 Middle Aged
 motor evoked potentials
 rehabilitation
 Retrospective Studies
 somatosensory evoked potentials
 Spinal Cord Ischemia
 Spinal infarct
K10plus-PPN:1578385601
Verknüpfungen:→ Zeitschrift

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