Oxidations with bonded salen-catalysts in microcapillaries

• Verfasst von: Sandel, Simone [VerfasserIn]
• Verfasst von: Weber, Sven K. [VerfasserIn]
• Verfasst von: Trapp, Oliver [VerfasserIn]
• Titel: Oxidations with bonded salen-catalysts in microcapillaries
• Verf.angabe: Simone Sandel, Sven K. Weber, Oliver Trapp
• Jahr: 2012
• Jahr des Originals: 2011
• Umfang: 9 S.
• Fussnoten: Available online 18 October 2011 ; Gesehen am 16.08.2018
• Titel Quelle: Enthalten in: Chemical engineering science
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1951
• Jahr Quelle: 2012
• Band/Heft Quelle: 83(2012), Seite 171-179
• DOI: doi:10.1016/j.ces.2011.10.034
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Catalysis
• Sach-SW: Microreactor
• Sach-SW: On-column reaction chromatography
• Sach-SW: Reaction kinetics
• Sach-SW: Salen immobilization
• Sach-SW: Sulfoxidation
• K10plus-PPN: 1580110274

Abstract

Chiral vanadium(IV)-salen complexes with variable spacer length were immobilized on polysiloxanes, which were used as catalytically active stationary phase in on-column reaction gas chromatography, on-column reaction electrophoresis, in flow-through reactors and as coating of laboratory glassware. These devices modified with the catalytically active stationary phase were employed in asymmetric sulfoxidations using hydrogen peroxide as the oxidant. The here presented approach combines catalysis and chromatographic analysis in a single step and allows to study the kinetics of reactions and to optimize reaction conditions. The initial reaction kinetics and enantioselectivity of the sulfoxidation of benzylphenylsulfide was studied in dependency of the spacer length of the immobilized salen ligand. A drastic influence of the spacer length on the enantioselectivity in the here investigated sulfoxidation was measured.