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Verfasst von:Ziesenitz, Victoria C. [VerfasserIn]   i
Titel:U.S. vaccine and immune globulin product shortages, 2001-15
Verf.angabe:Victoria C. Ziesenitz, Maryann Mazer-Amirshahi, Mark S. Zocchi, Erin R. Fox and Larissa S. May
Umfang:8 S.
Fussnoten:Gesehen am 17.08.2018
Titel Quelle:Enthalten in: American journal of health system pharmacy
Jahr Quelle:2017
Band/Heft Quelle:74(2017), 22, S. 1879-1886
ISSN Quelle:1535-2900
Abstract:Purpose Trends in shortages of vaccines and immune globulin products from 2001 through 2015 in the United States are described. - Methods Drug shortage data from January 2001 through December 2015 were obtained from the University of Utah Drug Information Service. Shortage data for vaccines and immune globulins were analyzed, focusing on the type of product, reason for shortage, shortage duration, shortages requiring vaccine deferral, and whether the drug was a single-source product. Inclusion of the product into the pediatric vaccination schedule was also noted. - Results Of the 2,080 reported drug shortages, 59 (2.8%) were for vaccines and immune globulin products. Of those, 2 shortages (3%) remained active at the end of the study period. The median shortage duration was 16.8 months. The most common products on shortage were viral vaccines (58%), especially hepatitis A, hepatitis B, rabies, and varicella vaccines (4 shortages each). A vaccine deferral was required for 21 shortages (36%), and single-source products were on shortage 30 times (51%). The most common reason for shortage was manufacturing problems (51%), followed by supply-and-demand issues (7%). Thirty shortages (51%) were for products on the pediatric schedule, with a median duration of 21.7 months. - Conclusion Drug shortages of vaccines and immune globulin products accounted for only 2.8% of reported drug shortages within a 15-year period, but about half of these shortages involved products on the pediatric vaccination schedule, which may have significant public health implications.
DOI:doi:10.2146/ajhp170066
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Verlag: http://dx.doi.org/10.2146/ajhp170066
 Verlag: http://www.ajhp.org/content/74/22/1879
 DOI: https://doi.org/10.2146/ajhp170066
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1580152872
Verknüpfungen:→ Zeitschrift

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