| |  Online-Ressource |
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| Verfasst von: | Attenberger, Ulrike [VerfasserIn]  |
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| | Meyer, Melissa [VerfasserIn] |
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| | Rathmann, Nils-Andreas [VerfasserIn] |
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| | Doyon, Fabian [VerfasserIn] |
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| | Kienle, Peter [VerfasserIn] |
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| | Hofheinz, Ralf-Dieter [VerfasserIn] |
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| | Pilz, Lothar R. [VerfasserIn] |
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| | Dinter, Dietmar [VerfasserIn] |
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| | Schönberg, Stefan [VerfasserIn] |
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| | Hausmann, Daniel [VerfasserIn] |
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| Titel: | mMRI at 3.0 T as an evaluation tool of therapeutic response to neoadjuvant CRT in patients with advanced-stage rectal cancer |
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| Verf.angabe: | Ulrike I. Attenberger, Melissa M. Ong, Nils Rathmann, Fabian Doyon, Peter Kienle, Ralf-Dieter Hofheinz, Lothar R. Pilz, Dietmar J. Dinter, Stefan O. Schoenberg, Daniel Hausmann |
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| Jahr: | 2017 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 21.08.2018 |
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| Titel Quelle: | Enthalten in: Anticancer research |
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| Ort Quelle: | Kapandriti, Attiki, Greece : International Institute of Anticancer Research, 2004 |
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| Jahr Quelle: | 2017 |
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| Band/Heft Quelle: | 37(2017), 1, Seite 215-222 |
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| ISSN Quelle: | 1791-7530 |
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| Abstract: | AIM: To assess whether multiparametric MRI (mMRI) can serve as a tool for evaluating response to chemoradiation therapy (CRT) in advanced-stage rectal cancer. PATIENTS AND METHODS: Twenty-one patients underwent a mMRI protocol at 3T before and after CRT. Two experienced radiologists evaluated the MRI measurements and inter-reader correlation was assessed. Changes in functional parameters in relation to regression, as well as pT stage were analyzed. The perfusion parameters plasma flow (PF) and mean transit time (MTT) were calculated offline using the established UMM Perfusion tool. RESULTS: Apparent diffusion coefficient values were significantly different among the different tumor RGs before CRT (p=0.041). Changes of dynamic contrast enhanced (DCE) MRI values did not reflect treatment response (PF: p=0.5; MTT: p=0.74). CONCLUSION: The results of our study population indicate that a high initial apparent diffusion coefficient value may be predictive of response to therapy following CRT. |
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| DOI: | doi:10.21873/anticanres.11309 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: http://dx.doi.org/10.21873/anticanres.11309 |
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| | DOI: https://doi.org/10.21873/anticanres.11309 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Adenocarcinoma |
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| | Aged |
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| | apparent diffusion coefficient |
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| | Chemoradiotherapy |
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| | dynamic contrast enhancement |
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| | Female |
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| | Humans |
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| | Magnetic Resonance Imaging |
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| | Male |
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| | Middle Aged |
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| | Multi-parametric MRI |
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| | Neoadjuvant Therapy |
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| | Neoplasm Staging |
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| | rectal cancer |
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| | Rectal Neoplasms |
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| | Treatment Outcome |
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| K10plus-PPN: | 1580242030 |
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| Verknüpfungen: | → Zeitschrift |
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mMRI at 3.0 T as an evaluation tool of therapeutic response to neoadjuvant CRT in patients with advanced-stage rectal cancer / Attenberger, Ulrike [VerfasserIn]; 2017 (Online-Ressource)
