Optic nerve head change in non-arteritic anterior ischemic optic neuropathy and its influence on visual outcome

• Verfasst von: Jonas, Jost B. [VerfasserIn]
• Verfasst von: Papastathopoulos, Konstantinos I. [VerfasserIn]
• Verfasst von: Rensch, Florian [VerfasserIn]
• Titel: Optic nerve head change in non-arteritic anterior ischemic optic neuropathy and its influence on visual outcome
• Verf.angabe: Jost B. Jonas, Scohan Singh Hayreh, Yong Tao, Konstantinos I. Papastathopoulos, Florian Rensch
• E-Jahr: 2012
• Jahr: May 21, 2012
• Umfang: 6 S.
• Fussnoten: Gesehen am 28.08.2018
• Titel Quelle: Enthalten in: PLOS ONE
• Ort Quelle: San Francisco, California, US : PLOS, 2006
• Jahr Quelle: 2012
• Band/Heft Quelle: 7(2012,5) Artikel-Nummer e37499, 6 Seiten
• ISSN Quelle: 1932-6203
• DOI: doi:10.1371/journal.pone.0037499
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Atrophy
• Sach-SW: Eyes
• Sach-SW: Glaucoma
• Sach-SW: Optic disc
• Sach-SW: Optic nerve
• Sach-SW: Optic neuropathy
• Sach-SW: Vision
• Sach-SW: Visual acuity
• K10plus-PPN: 1580480128

Abstract

Purpose To evaluate changes in cup/disc (C/D) diameter ratios and parapapillary atrophy in patients with non-arteritic anterior ischemic optic neuropathy (NA-AION), using morphometric methods. Methods The clinical non-interventional study included 157 patients with unilateral or bilateral NA-AION. Optic disc photographs taken from both eyes at the end of follow-up were morphometrically examined. Results Follow-up was 86.3±70.3 months. Horizontal and vertical disc diameters (P = 0.30;P = 0.61, respectively), horizontal and vertical C/D ratios (P = 0.47;P = 0.19,resp.), and size of alpha zone and beta zone of parapapillary atrophy (P = 0.27;P = 0.32,resp.) did not differ significantly between affected eyes and contralateral normal eyes in patients with unilateral NA-AION. Similarly, horizontal and vertical disc diameters, horizontal and vertical C/D ratios, and size of alpha zone and beta zone did not vary significantly (all P>0.05) between the unaffected eyes of patients with unilateral NA-AION and the eyes of patients with bilateral NA-AION. Optic disc diameters, C/D ratios, size of alpha zone or beta zone of parapapillary atrophy were not significantly associated with final visual outcome in the eyes affected with NA-AION (all P>0.20) nor with the difference in final visual acuity between affected eyes and unaffected eyes in patients with unilateral NA-AION (all P>0.25). Conclusions NA-AION did not affect C/D ratios nor alpha zone and beta zone of parapapillary atrophy. Optic disc size was not related to the final visual acuity outcome in NA-AION.