Vitamin D and chronic diseases

• Verfasst von: Muscogiuri, Giovanna [VerfasserIn]
• Verfasst von: März, Winfried [VerfasserIn]
• Titel: Vitamin D and chronic diseases
• Titelzusatz: the current state of the art
• Verf.angabe: Giovanna Muscogiuri, Barbara Altieri, Cedric Annweiler, Giancarlo Balercia, H.B. Pal, Barbara J. Boucher, John J. Cannell, Carlo Foresta, Martin R. Grübler, Kalliopi Kotsa, Luca Mascitelli, Winfried März, Francesco Orio, Stefan Pilz, Giacomo Tirabassi, Annamaria Colao
• Jahr: 2017
• Jahr des Originals: 2016
• Umfang: 11 S.
• Fussnoten: First online: 18 July 2016 ; Gesehen am 29.08.2018
• Titel Quelle: Enthalten in: Archives of toxicology
• Ort Quelle: Berlin : Springer, 1930
• Jahr Quelle: 2017
• Band/Heft Quelle: 91(2017), 1, Seite 97-107
• ISSN Quelle: 1432-0738
• DOI: doi:10.1007/s00204-016-1804-x
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Autism
• Sach-SW: Cancer
• Sach-SW: Cardiovascular diseases
• Sach-SW: Dementia
• Sach-SW: Diabetes mellitus
• Sach-SW: Endometriosis
• Sach-SW: Environment
• Sach-SW: Fertility
• Sach-SW: Hypogonadism
• Sach-SW: Lifestyle
• Sach-SW: Musculoskeletal disorders
• Sach-SW: PCOS
• Sach-SW: Vitamin D
• K10plus-PPN: 1580503721

Abstract

The objective was to provide the current state of the art regarding the role of vitamin D in chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 and type 2 diabetes mellitus, male and female fertility). The document was drawn up by panelists that provided their contribution according to their own scientific expertise. Each scientific expert supplied a first draft manuscript on a specific aspect of the document’s topic that was subjected to voting by all experts as “yes” (agreement with the content and/or wording) or “no” (disagreement). The adopted rule was that statements supported by ≥75 % of votes would be immediately accepted, while those with <25 % would be rejected outright. Others would be subjected to further discussion and subsequent voting, where ≥67 % support or, in an eventual third round, a majority of ≥50 % would be needed. This document finds that the current evidence support a role for vitamin D in bone health but not in other health conditions. However, subjects with vitamin D deficiency have been found to be at high risk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommend vitamin D supplementation as treatment of chronic diseases, the treatment of vitamin D deficiency should be desiderable in order to reduce the risk of developing chronic diseases.