Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Tripp, Joanna [VerfasserIn]  |
| König, Patrick [VerfasserIn]  |
| Sinning, Irmgard [VerfasserIn]  |
| Tews, Ivo [VerfasserIn]  |
Titel: | Structure and conservation of the periplasmic targeting factor Tic22 protein from plants and cyanobacteria |
Verf.angabe: | Joanna Tripp, Alexander Hahn, Patrick Koenig, Nadine Flinner, Daniela Bublak, Eva M. Brouwer, Franziska Ertel, Oliver Mirus, Irmgard Sinning, Ivo Tews, and Enrico Schleiff |
Umfang: | 10 S. |
Fussnoten: | Gesehen am 29.08.2018 |
Titel Quelle: | Enthalten in: The journal of biological chemistry |
Jahr Quelle: | 2012 |
Band/Heft Quelle: | 287(2012), 29, S. 24164-24173 |
ISSN Quelle: | 1083-351X |
Abstract: | Mitochondria and chloroplasts are of endosymbiotic origin. Their integration into cells entailed the development of protein translocons, partially by recycling bacterial proteins. We demonstrate the evolutionary conservation of the translocon component Tic22 between cyanobacteria and chloroplasts. Tic22 in Anabaena sp. PCC 7120 is essential. The protein is localized in the thylakoids and in the periplasm and can be functionally replaced by a plant orthologue. Tic22 physically interacts with the outer envelope biogenesis factor Omp85 in vitro and in vivo, the latter exemplified by immunoprecipitation after chemical cross-linking. The physical interaction together with the phenotype of a tic22 mutant comparable with the one of the omp85 mutant indicates a concerted function of both proteins. The three-dimensional structure allows the definition of conserved hydrophobic pockets comparable with those of ClpS or BamB. The results presented suggest a function of Tic22 in outer membrane biogenesis. |
DOI: | doi:10.1074/jbc.M112.341644 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Kostenfrei: Verlag: http://dx.doi.org/10.1074/jbc.M112.341644 |
| Kostenfrei: Verlag: http://www.jbc.org/content/287/29/24164 |
| DOI: https://doi.org/10.1074/jbc.M112.341644 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1580519768 |
Verknüpfungen: | → Zeitschrift |
Structure and conservation of the periplasmic targeting factor Tic22 protein from plants and cyanobacteria / Tripp, Joanna [VerfasserIn] (Online-Ressource)
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