| |  Online-Ressource |
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| Verfasst von: | Haberlandt, Edda [VerfasserIn]  |
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| | Plecko, Barbara [VerfasserIn] |
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| | Schubert-Bast, Susanne [VerfasserIn] |
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| Titel: | Epileptic phenotypes, electroclinical features and clinical characteristics in 17 children with anti-NMDAR encephalitis |
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| Verf.angabe: | E. Haberlandt, M. Ensslen, U. Gruber-Sedlmayr, B. Plecko, M. Brunner-Krainz, M. Schimmel, S. Schubert-Bast, U. Neirich, H. Philippi, G. Kurleman, M. Tardieu, G. Wohlrab, I. Borggraefe, K. Rostásy |
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| Jahr: | 2017 |
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| Jahr des Originals: | 2016 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 04.09.2018 ; Available online 5 December 2016 |
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| Titel Quelle: | Enthalten in: European journal of paediatric neurology |
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| Ort Quelle: | Burlington, Mass. : Harcourt, 1997 |
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| Jahr Quelle: | 2017 |
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| Band/Heft Quelle: | 21(2017), 3, Seite 457-464 |
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| ISSN Quelle: | 1532-2130 |
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| Abstract: | Background: Anti-N-methyl d-aspartate receptor (NMDAR) encephalitis is a rare disorder characterized by seizures, neuropsychiatric symptoms, dyskinesia and autonomic instability. Objective: Aim of the present study was to evaluate the seizure phenotypes and electroencephalogram (EEG) features in children with anti-NMDAR encephalitis. Methods: Seizure types, electroclinical features and clinical characteristics of 17 children with anti-NMDAR encephalitis were analysed in a retrospective case series from nine centres in Europe. Results: Nearly half (8/17) of the children presented with psychiatric symptoms, whereas in 4/17 patients seizures were the first symptom and in 5/17 both symptoms occurred at the same time. During the following course seizures were reported in 16/17 children. The first EEG detected generalized slowing in 11/17 patients, focal slowing in 3/17 and normal background activity in only 3/17 children. The extreme delta brush (EDB) pattern was detected in 9/17 (53%) patients. Conclusion: In addition to psychiatric symptoms, children with anti-NMDAR encephalitis often show generalized slowing in EEG with or without seizures at initial presentation. EDB is present in half of all children and is potentially a helpful tool for early detection of this immune-mediated disease. |
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| DOI: | doi:10.1016/j.ejpn.2016.11.016 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1016/j.ejpn.2016.11.016 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S109037981630246X |
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| | DOI: https://doi.org/10.1016/j.ejpn.2016.11.016 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Children |
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| | Anti-NMDAR encephalitis |
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| | Delta brush |
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| | Epilepsy |
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| | Extreme |
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| | Focal seizures |
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| | Generalized seizures |
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| K10plus-PPN: | 1580675212 |
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| Verknüpfungen: | → Zeitschrift |
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Epileptic phenotypes, electroclinical features and clinical characteristics in 17 children with anti-NMDAR encephalitis / Haberlandt, Edda [VerfasserIn]; 2017 (Online-Ressource)
