| |  Online-Ressource |
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| Verfasst von: | Naumann, Patrick [VerfasserIn]  |
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| | Liermann, Jakob [VerfasserIn] |
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| | Fortunato, Franco [VerfasserIn] |
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| | Weber, Klaus-Josef [VerfasserIn] |
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| | Debus, Jürgen [VerfasserIn] |
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| Titel: | Sulforaphane enhances irradiation effects in terms of perturbed cell cycle progression and increased DNA damage in pancreatic cancer cells |
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| Verf.angabe: | Patrick Naumann, Jakob Liermann, Franco Fortunato, Thomas E. Schmid, Klaus-Josef Weber, Jürgen Debus, Stephanie E. Combs |
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| E-Jahr: | 2017 |
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| Jahr: | July 10, 2017 |
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| Umfang: | 13 S. |
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| Teil: | volume:12 |
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| | year:2017 |
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| | number:7 |
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| | elocationid:e0180940 |
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| | extent:13 |
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| Fussnoten: | Gesehen am 26.09.2018 |
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| Titel Quelle: | Enthalten in: PLOS ONE |
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| Ort Quelle: | San Francisco, California, US : PLOS, 2006 |
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| Jahr Quelle: | 2017 |
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| Band/Heft Quelle: | 12(2017), 7, Artikel-ID e0180940 |
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| ISSN Quelle: | 1932-6203 |
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| Abstract: | Sulforaphane (SFN), an herbal isothiocyanate enriched in cruciferous vegetables like broccoli and cauliflower, has gained popularity for its antitumor effects in cell lines such as pancreatic cancer. Antiproliferative as well as radiosensitizing properties were reported for head and neck cancer but little is known about its effects in pancreatic cancer cells in combination with irradiation (RT). In four established pancreatic cancer cell lines we investigated clonogenic survival, analyzed cell cycle distribution and compared DNA damage via flow cytometry and western blot after treatment with SFN and RT. |
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| DOI: | doi:10.1371/journal.pone.0180940 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Kostenfrei: Volltext ; Verlag: http://dx.doi.org/10.1371/journal.pone.0180940 |
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| | Kostenfrei: Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180940 |
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| | DOI: https://doi.org/10.1371/journal.pone.0180940 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Cancer treatment |
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| | Cell cycle and cell division |
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| | Cell cycle inhibitors |
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| | DNA damage |
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| | DNA repair |
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| | Non-homologous end joining |
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| | Pancreatic cancer |
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| | Radiation therapy |
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| K10plus-PPN: | 1581340907 |
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| Verknüpfungen: | → Zeitschrift |
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Sulforaphane enhances irradiation effects in terms of perturbed cell cycle progression and increased DNA damage in pancreatic cancer cells / Naumann, Patrick [VerfasserIn]; July 10, 2017 (Online-Ressource)
