Complication rates of catheter ablation of atrial fibrillation in patients aged ≥75 years versus <75 years

• Verfasst von: Moser, Julia Magdalena [VerfasserIn]
• Verfasst von: Schumacher, Burghard [VerfasserIn]
• Titel: Complication rates of catheter ablation of atrial fibrillation in patients aged ≥75 years versus <75 years
• Titelzusatz: results from the German Ablation Registry
• Verf.angabe: Julia M. Moser, M.D., Stephan Willems, M.D., Dietrich Andresen, M.D., Johannes Brachmann, M.D., Lars Eckardt, M.D., Ellen Hoffmann, M.D., Karl-Heinz Kuck, M.D., Thorsten Lewalter, M.D., Burghard Schumacher, M.D., Stefan G. Spitzer, M.D., Matthias Hochadel, M.Sc., Jochen Senges, M.D., and Boris A. Hoffmann, M.D.
• Jahr: 2017
• Jahr des Originals: 2016
• Umfang: 8 S.
• Fussnoten: 07 December 2016 ; Gesehen am 27.09.2018
• Titel Quelle: Enthalten in: Journal of cardiovascular electrophysiology
• Ort Quelle: Oxford : Wiley-Blackwell, 1990
• Jahr Quelle: 2017
• Band/Heft Quelle: 28(2017), 3, Seite 258-265
• ISSN Quelle: 1540-8167
• DOI: doi:10.1111/jce.13142
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: age
• Sach-SW: atrial fibrillation
• Sach-SW: catheter ablation
• Sach-SW: complications
• Sach-SW: stroke
• K10plus-PPN: 1581352859

Abstract

Introduction Despite a rising demand for catheter ablation (CA) of atrial fibrillation (AF) in an elderly population, complication and success rates are not fully elucidated. We sought to compare complication rates of CA of AF in patients ≥75 versus <75 years of age. Methods and Results Patients with symptomatic, drug-refractory AF were prospectively enrolled from January 2007 to 2010 in this multicenter study. A total of 4,449 patients, group 1 ≥75 years and group 2 <75 years (n = 227, age 77.3 ± 2.2 vs. 59.7 ± 9.8 years, 52.0% vs. n = 4,222, 68.9% male, CHA2DS2-VASc-Score 3.7 ± 1.0 vs. 1.7 ± 1.2; P < 0.001, respectively), with paroxysmal AF (59.9% in group 1 vs. 63.3% in group 2, P = 0.30), and persistent AF (34.8% in group 1 vs. 29.4% in group 2, P = 0.082) underwent CA of AF. A centralized follow-up was obtained in 4,347 patients by the Institute for Myocardial Infarction Research (IHF, Ludwigshafen). There was a significant difference between periprocedural stroke rates in the elderly versus the younger cohort (1.3% vs. 0.1%, P < 0.01). In-hospital severe nonfatal complications did not differ significantly between the groups (4.4% vs. 2.7%, P = 0.14). Other procedure-related, in-hospital complications were not significantly different. After a mean follow-up of 472 ± 99 days (group 1) and 477 ± 94 days (group 2), no differences were found in complication rates. Conclusion CA of AF in patients ≥75 years is associated with higher in-hospital stroke rates. In a 1-year follow-up, complication rates do not differ between the groups.