Absorbable implant to treat nasal valve collapse

• Verfasst von: San Nicoló, Marion Sandra [VerfasserIn]
• Verfasst von: Sadick, Haneen [VerfasserIn]
• Titel: Absorbable implant to treat nasal valve collapse
• Verf.angabe: Marion San Nicoló, MD, Klaus Stelter, MD, Haneen Sadick, MD, Murat Bas, MD, Alexander Berghaus, MD
• Jahr: 2017
• Umfang: 8 S.
• Fussnoten: Gesehen am 12.10.2018
• Titel Quelle: Enthalten in: Facial plastic surgery
• Ort Quelle: New York, NY : Thieme Medical Publ., 1983
• Jahr Quelle: 2017
• Band/Heft Quelle: 33(2017), 2, Seite 233-240
• ISSN Quelle: 1098-8793
• DOI: doi:10.1055/s-0037-1598655
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1581853998

Abstract

Objective: To evaluate the safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with nasal valve collapse (NVC) with 12 months follow-up. Methods: Thirty subjects with Nasal Obstruction Symptom Evaluation (NOSE) score ≥ 55 and isolated NVC were treated; 14 cases were performed in an operating suite under general anesthesia and 16 cases were performed in a clinic-based setting under local anesthesia. The implant, a polylactic acid copolymer, was placed with a delivery tool within the nasal wall to provide lateral cartilage support. Subjects were followed up through 12 months postprocedure. Results: Fifty-six implants were placed in 30 subjects. The mean preoperative NOSE score was 76.7 ± 14.8, with a range of 55 to 100. At 12 months, the mean score was 35.2 ± 29.2, reflecting an average within-patient reduction of -40.9 ± 31.2 points. The majority (76%) of the subjects were responders defined as having at least one NOSE class improvement or a NOSE score reduction of at least 20%. There were no adverse changes in cosmetic appearance at 12 months postprocedure. Three implants in three subjects required retrieval within 30 days postprocedure and resulted in no clinical sequelae. Conclusion: This study demonstrates safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with NVC at 12 months postprocedure.