Navigation bronchoscopy-guided radiofrequency ablation for nonsurgical peripheral pulmonary tumors

• Verfasst von: Xie, Fangfang [VerfasserIn]
• Verfasst von: Herth, Felix [VerfasserIn]
• Titel: Navigation bronchoscopy-guided radiofrequency ablation for nonsurgical peripheral pulmonary tumors
• Verf.angabe: Fangfang Xie, Xiaoxuan Zheng, Bo Xiao, Baohui Han, Felix J. F. Herth, Jiayuan Sun
• Jahr: 2017
• Umfang: 6 S.
• Teil: volume:94
• Teil: year:2017
• Teil: number:3
• Teil: pages:293-298
• Teil: extent:6
• Fussnoten: Published online: July 06, 2017 ; Gesehen am 22.10.2018
• Titel Quelle: Enthalten in: Respiration
• Ort Quelle: Basel : Karger, 1944
• Jahr Quelle: 2017
• Band/Heft Quelle: 94(2017), 3, Seite 293-298
• ISSN Quelle: 1423-0356
• DOI: doi:10.1159/000477764
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1582161003

Abstract

We have recently developed a flexible catheter electrode used for bronchoscopic radiofrequency ablation (RFA). Two patients with nonsurgical stage IA peripheral lung cancer and 1 with lung metastasis underwent treatment with flexible catheter RFA utilizing navigation bronchoscopy. Chest computed tomography (CT) and positron emission tomography/CT (PET/CT) were performed before and after RFA to assess the ablation response of the patients. One patient's tumor had no prior PET uptake and therefore no follow-up PET was obtained. The first and the third patient obtained partial response to RFA, and the second patient obtained complete response 3 months after RFA. The first patient developed progressive disease 6 months after RFA. The second and the third patient achieved one-year progression-free survival. No significant complications occurred in the 3 patients. Navigation bronchoscopy-guided RFA is a safe and feasible procedure for poor surgical candidates with stage IA lung cancer or lung metastasis.