Fertility protection

• Verfasst von: Beckmann, Matthias Wilhelm [VerfasserIn]
• Verfasst von: Sütterlin, Marc [VerfasserIn]
• Verfasst von: Germeyer, Ariane [VerfasserIn]
• Titel: Fertility protection
• Titelzusatz: complications of surgery and results of removal and transplantation of ovarian tissue
• Verf.angabe: Matthias W. Beckmann, Ralf Dittrich, Laura Lotz, Karin van der Ven, Hans H. van der Ven, Jana Liebenthron, Matthias Korell, Torsten Frambach, Marc Sütterlin, Roxana Schwab, Stefan Seitz, Andreas Müller, Michael von Wolff, Felix Häberlin, Melanie Henes, Katharina Winkler-Crepaz, Jan S. Krüssel, Ariane Germeyer, Bettina Toth
• E-Jahr: 2018
• Jahr: February 2018
• Umfang: 9 S.
• Fussnoten: Available online 9 November 2017 ; Gesehen am 02.11.2018
• Titel Quelle: Enthalten in: Reproductive biomedicine online
• Ort Quelle: Cambridge : [Verlag nicht ermittelbar], 2000
• Jahr Quelle: 2018
• Band/Heft Quelle: 36(2018), 2, Seite 188-196
• ISSN Quelle: 1472-6491
• DOI: doi:10.1016/j.rbmo.2017.10.109
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: cancer
• Sach-SW: fertility preservation
• Sach-SW: oncofertility
• Sach-SW: ovarian tissue
• Sach-SW: transplantation
• K10plus-PPN: 1582529876

Abstract

Fertility-preserving measures are becoming important for patients receiving oncological treatment. One method involves cryopreservation of ovarian tissue and transplanting it when treatment is completed. We report complications resulting from surgical and fertility medicine, and the results of procedures for the removal and transplantation of ovarian tissue carried out within the FertiProtekt network. A survey using a structured questionnaire was conducted among the FertiProtekt network centres between November 2015 and June 2016. The analysis included surgical techniques used to remove and transplant ovarian tissue, surgical complications and results. Laparoscopic removal and transplantation of ovarian tissue have a low risk of complications. Surgical complications occurred in three of the network's 1373 ovarian tissue removals (n = 1302) and transplantations (n = 71); two complications (0.2%) occurred during removal and one during transplantation. Menstruation resumed in 47 out of 58 women (81%) who underwent ovarian tissue transplantation. Hormonal activity occurred in 63.2% of transplantations with a follow-up of 6 months or over. Sixteen pregnancies occurred in 14 patients, with nine births. The risks and complications of removal and transplantation of ovarian tissue are similar to those of standard laparoscopy. These procedures are becoming standard for fertility protection in cancer patients.