| |  Online-Ressource |
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| Verfasst von: | Becker-Grünig, Tabea [VerfasserIn]  |
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| | Benjamin, Nicola [VerfasserIn] |
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| | Lichtblau, Mona [VerfasserIn] |
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| | Nagel, Christian [VerfasserIn] |
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| | Fischer, Christine [VerfasserIn] |
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| | Gorenflo, Matthias [VerfasserIn] |
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| | Grünig, Ekkehard [VerfasserIn] |
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| Titel: | Efficacy of exercise training in pulmonary arterial hypertension associated with congenital heart disease |
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| Verf.angabe: | Tabea Becker-Grünig, Hans Klose, Nicola Ehlken, Mona Lichtblau, Christian Nagel, Christine Fischer, Matthias Gorenflo, Henning Tiede, Dietmar Schranz, Alfred Hager, Harald Kaemmerer, Oliver Miera, Silvia Ulrich, Rudolf Speich, Sören Uiker, Ekkehard Grünig |
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| E-Jahr: | 2013 |
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| Jahr: | 20 September 2013 |
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| Umfang: | 7 S. |
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| Fussnoten: | Available online 5 October 2012 ; Gesehen am 05.11.2018 |
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| Titel Quelle: | Enthalten in: International journal of cardiology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1981 |
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| Jahr Quelle: | 2013 |
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| Band/Heft Quelle: | 168(2013), 1, Seite 375-381 |
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| ISSN Quelle: | 1874-1754 |
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| Abstract: | Background: The objective of this prospective study was to assess the efficacy of exercise training as add-on to medical therapy in patients with congenital heart disease associated pulmonary arterial hypertension (CHD-APAH). Methods: Patients with invasively confirmed CHD-APAH received in-hospital exercise training for 3weeks and continued at home. Efficacy parameters were evaluated at baseline, after 3 and 15weeks. Medical treatment remained unchanged. Worsening events and survival rate were assessed in a follow-up period of 21±14months. Results: Twenty consecutive CHD-APAH patients (16 female, 4 male, mean pulmonary arterial pressure 60±23mmHg) were included. Patients significantly improved the mean distance walked in 6min compared to baseline by 63±47m after 3weeks (p<0.001) and by 67±59m after 15weeks (p=0.001). Quality of life-score (p=0.05), peak oxygen consumption (p=0.002) and maximal workload (p=0.003) improved significantly by exercise training after 15weeks. The 1- and 2‐year survival rates were 100%, the transplantation-free survival rate was 100% after 1year and 93% after 2years. Conclusion: Exercise training as add-on to medical therapy may be effective in patients with CHD-APAH and improved work capacity, quality of life and further prognostic relevant parameters. It was associated with an excellent long-term survival. Further randomized controlled studies are needed to confirm these results. |
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| DOI: | doi:10.1016/j.ijcard.2012.09.036 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1016/j.ijcard.2012.09.036 |
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| | Volltext: http://www.sciencedirect.com/science/article/pii/S0167527312011424 |
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| | DOI: https://doi.org/10.1016/j.ijcard.2012.09.036 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Congenital heart disease |
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| | Exercise training |
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| | Pulmonary hypertension |
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| | Rehabilitation |
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| K10plus-PPN: | 1582570833 |
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| Verknüpfungen: | → Zeitschrift |
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Efficacy of exercise training in pulmonary arterial hypertension associated with congenital heart disease / Becker-Grünig, Tabea [VerfasserIn]; 20 September 2013 (Online-Ressource)
