Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Giesen, Nicola [VerfasserIn]   i
 Goldschmidt, Hartmut [VerfasserIn]   i
 Raab, Marc-Steffen [VerfasserIn]   i
Titel:Management of high-risk Myeloma
Titelzusatz:an evidence-based review of treatment strategies
Verf.angabe:Nicola Lehners, Patrick J. Hayden, Hartmut Goldschmidt & Marc-Steffen Raab
E-Jahr:2016
Jahr:4 July 2016
Umfang:13 S.
Fussnoten:Gesehen am 13.11.2018
Titel Quelle:Enthalten in: Expert review of hematology
Ort Quelle:Abingdon, Oxon : Taylor & Francis, 2008
Jahr Quelle:2016
Band/Heft Quelle:9(2016), 8, Seite 753-765
ISSN Quelle:1747-4094
Abstract:Introduction: Despite the progress made in the treatment of patients with multiple myeloma over recent decades, a significant cohort with high-risk disease as defined by specific clinical and genetic criteria continue to respond poorly to standard treatment. These patients represent a particular challenge to the treating physician and require early identification as well as personalized treatment strategies.Areas covered: In this review, we discuss the prognostic impact of adverse clinical, radiological and genetic factors, evaluate available scoring systems and highlight key aspects of the therapeutic management of high-risk myeloma. MEDLINE and recent scientific meetings’ databases were searched for the keywords ‘high-risk’ and ‘multiple myeloma’ and relevant studies relating to both diagnostic and therapeutic approaches were identified.Expert commentary: A case is made for intensive induction using combinations of novel agents, early high-dose therapy supported by autologous stem cell transplantation and the widespread use of maintenance therapies. Novel therapeutic options, especially in the field of immunotherapy, are currently explored in clinical trials and have the potential to further improve outcomes for patients with high-risk multiple myeloma.
DOI:doi:10.1080/17474086.2016.1204908
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: http://dx.doi.org/10.1080/17474086.2016.1204908
 Volltext: https://doi.org/10.1080/17474086.2016.1204908
 DOI: https://doi.org/10.1080/17474086.2016.1204908
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:allogeneic transplantation
 autologous transplantation
 high-risk myeloma
 maintenance therapy
 Multiple myeloma
 novel agents
 risk factors
K10plus-PPN:1583651381
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68327753   QR-Code
zum Seitenanfang