| |  Online-Ressource |
|---|
| Verfasst von: | Hwang, Eugene [VerfasserIn]  |
|---|
| | Kool, Marcel [VerfasserIn] |
|---|
| | Capper, David [VerfasserIn] |
|---|
| | Chavez, Lukas [VerfasserIn] |
|---|
| | Deimling, Andreas von [VerfasserIn] |
|---|
| | Jones, David T. W. [VerfasserIn] |
|---|
| | Pfister, Stefan [VerfasserIn] |
|---|
| | Brabetz, Sebastian [VerfasserIn] |
|---|
| Titel: | Extensive molecular and clinical heterogeneity in patients with histologically diagnosed cns-pnet treated as a single entity |
|---|
| Titelzusatz: | a report from the children’s oncology group randomized ACNS0332 trial |
|---|
| Verf.angabe: | Eugene I. Hwang, Marcel Kool, Peter C. Burger, David Capper, Lukas Chavez, Sebastian Brabetz, Chris Williams-Hughes, Catherine Billups, Linda Heier, Alok Jaju, Jeff Michalski, Yimei Li, Sarah Leary, Tianni Zhou, Andreas von Deimling, David T.W. Jones, Maryam Fouladi, Ian F. Pollack, Amar Gajjar, Roger J. Packer, Stefan M. Pfister, and James M. Olson |
|---|
| E-Jahr: | 2018 |
|---|
| Jahr: | December 1, 2018 |
|---|
| Umfang: | 8 S. |
|---|
| Fussnoten: | Gesehen am 27.11.2018 |
|---|
| Titel Quelle: | Enthalten in: Journal of clinical oncology |
|---|
| Ort Quelle: | Alexandria, Va. : American Society of Clinical Oncology, 1983 |
|---|
| Jahr Quelle: | 2018 |
|---|
| Band/Heft Quelle: | 36(2018), 34, Seite 3388-3395 |
|---|
| ISSN Quelle: | 1527-7755 |
|---|
| Abstract: | Children with histologically diagnosed high-risk medulloblastoma, supratentorial primitive neuroectodermal tumor of the CNS (CNS-PNET), and pineoblastoma (PBL) have had poor survival despite intensive treatment. We included these patients in this Children’s Oncology Group trial. Molecular profiling later revealed tumor heterogeneity that was not detectable at protocol inception. Enrollment of patients with CNS-PNET/PBL was subsequently discontinued, and outcomes for this part of the study are reported here. |
|---|
| DOI: | doi:10.1200/JCO.2017.76.4720 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: http://dx.doi.org/10.1200/JCO.2017.76.4720 |
|---|
| | Volltext: http://ascopubs.org/doi/10.1200/JCO.2017.76.4720 |
|---|
| | DOI: https://doi.org/10.1200/JCO.2017.76.4720 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| K10plus-PPN: | 1584499524 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Extensive molecular and clinical heterogeneity in patients with histologically diagnosed cns-pnet treated as a single entity / Hwang, Eugene [VerfasserIn]; December 1, 2018 (Online-Ressource)
