Prostate cancer molecular imaging standardized evaluation (PROMISE)

• Verfasst von: Eiber, Matthias [VerfasserIn]
• Verfasst von: Giesel, Frederik L. [VerfasserIn]
• Titel: Prostate cancer molecular imaging standardized evaluation (PROMISE)
• Titelzusatz: proposed miTNM classification for the interpretation of PSMA-ligand PET/CT
• Verf.angabe: Matthias Eiber, Ken Herrmann, Jeremie Calais, Boris Hadaschik, Frederik L. Giesel, Markus Hartenbach, Thomas Hope, Robert Reiter, Tobias Maurer, Wolfgang A. Weber, and Wolfgang P. Fendler
• E-Jahr: 2018
• Jahr: March 1, 2018
• Umfang: 10 S.
• Fussnoten: Published online Nov. 9, 2017 ; Gesehen am 28.11.2018
• Titel Quelle: Enthalten in: Journal of nuclear medicine
• Ort Quelle: New York, NY : Soc., 1964
• Jahr Quelle: 2018
• Band/Heft Quelle: 59(2018), 3, Seite 469-478
• ISSN Quelle: 2159-662X
• ISSN Quelle: 1535-5667
• DOI: doi:10.2967/jnumed.117.198119
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: criteria
• Sach-SW: interpretation
• Sach-SW: miTNM
• Sach-SW: PROMISE
• Sach-SW: PSMA-ligand PET/CT
• Sach-SW: standardized evaluation
• K10plus-PPN: 1584610263

Abstract

Prostate-specific membrane antigen (PSMA)-ligand PET imaging provides unprecedented accuracy for whole-body staging of prostate cancer. As PSMA-ligand PET/CT is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. We propose a molecular imaging TNM system (miTNM, version 1.0) as a standardized reporting framework for PSMA-ligand PET/CT or PET/MRI. miTNM is designed to organize findings in comprehensible categories to promote the exchange of information among physicians and institutions. Additionally, flowcharts integrating findings of PSMA-ligand PET and morphologic imaging have been designed to guide image interpretation. Specific applications, such as assessment of prognosis or impact on management, should be evaluated in future trials. miTNM is a living framework that evolves with clinical experience and scientific data.