| |  Online-Ressource |
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| Verfasst von: | Weis, Cleo-Aron Thias [VerfasserIn]  |
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| | Kather, Jakob Nikolas [VerfasserIn] |
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| | Melchers, Susanne [VerfasserIn] |
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| | Al-ahmdi, Hanaa [VerfasserIn] |
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| | Gaiser, Timo [VerfasserIn] |
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| Titel: | Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome |
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| Verf.angabe: | Cleo-Aron Weis, Jakob Nikolas Kather, Susanne Melchers, Hanaa Al-ahmdi, Marion J. Pollheimer, Cord Langner and Timo Gaiser |
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| E-Jahr: | 2018 |
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| Jahr: | 28 August 2018 |
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| Umfang: | 12 S. |
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| Fussnoten: | Gesehen am 24.01.2019 |
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| Titel Quelle: | Enthalten in: Diagnostic pathology |
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| Ort Quelle: | [Erscheinungsort nicht ermittelbar] : BioMed Central, 2006 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 13(2018), Artikel-ID 64, Seite 1-12 |
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| ISSN Quelle: | 1746-1596 |
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| Abstract: | Tumor budding, meaning a detachment of tumor cells at the invasion front of colorectal carcinoma (CRC) into single cells or clusters (<=5 tumor cells), has been shown to correlate to an inferior clinical outcome by several independent studies. Therefore, it has been discussed as a complementary prognostic factor to the TNM staging system, and it is already included in national guidelines as an additional prognostic parameter. However, its application by manual evaluation in routine pathology is hampered due to the use of several slightly different assessment systems, a time-consuming manual counting process and a high inter-observer variability. Hence, we established and validated an automatic image processing approach to reliably quantify tumor budding in immunohistochemically (IHC) stained sections of CRC samples. |
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| DOI: | doi:10.1186/s13000-018-0739-3 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: http://dx.doi.org/10.1186/s13000-018-0739-3 |
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| | kostenfrei: Volltext: https://doi.org/10.1186/s13000-018-0739-3 |
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| | DOI: https://doi.org/10.1186/s13000-018-0739-3 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Bibliogr. Hinweis: | Forschungsdaten: Weis, Cleo-Aron Thias, 1985 - : Automatic evaluation of tumour budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome [dataset] |
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| K10plus-PPN: | 1586549081 |
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| Verknüpfungen: | → Zeitschrift |
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Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome / Weis, Cleo-Aron Thias [VerfasserIn]; 28 August 2018 (Online-Ressource)
