Ventral striatum connectivity during reward anticipation in adolescent smokers

• Verfasst von: Jollans, Lee [VerfasserIn]
• Verfasst von: Banaschewski, Tobias [VerfasserIn]
• Verfasst von: Flor, Herta [VerfasserIn]
• Titel: Ventral striatum connectivity during reward anticipation in adolescent smokers
• Verf.angabe: Lee Jollans, Cao Zhipeng, Ilknur Icke, Ciara Greene, Clare Kelly, Tobias Banaschewski, Arun L. W. Bokde, Uli Bromberg, Christian Büchel, Anna Cattrell, Patricia J. Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Michael N. Smolka, Henrik Walter, Gunter Schumann and Robert Whelan
• E-Jahr: 2016
• Jahr: 13 Apr 2016
• Umfang: 16 S.
• Fussnoten: Gesehen am 07.02.2019
• Titel Quelle: Enthalten in: Developmental neuropsychology
• Ort Quelle: New York, NY [u.a.] : Psychology Press, Taylor & Francis Group, 1985
• Jahr Quelle: 2016
• Band/Heft Quelle: 41(2016), 1-2, Seite 6-21
• ISSN Quelle: 1532-6942
• DOI: doi:10.1080/87565641.2016.1164172
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1587354837

Abstract

Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.