Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Schlehofer, Brigitte [VerfasserIn]   i
 Wahrendorf, Jürgen [VerfasserIn]   i
Titel:Role of medical history in brain tumour development. Results from the international adult brain tumour study
Verf.angabe:Brigitte Schlehofer, Maria Blettner, Susan Preston‐Martin, Dorothea Niehoff, Jürgen Wahrendorf, Annie Arslan, Anders Ahlbom, Won N. Choi, Graham G. Giles, Geoffrey R. Howe, Julian Little, Francois Ménégoz and Philip Ryan
Umfang:6 S.
Fussnoten:Gesehen am 11.02.2019
Titel Quelle:Enthalten in: International journal of cancer
Jahr Quelle:1999
Band/Heft Quelle:82(1999), 2, S. 155-160
ISSN Quelle:1097-0215
Abstract:In an international population-based case-control study carried out in 8 centres in 6 countries, we investigated the role of specific medical conditions in the aetiology of brain tumours in adults. Recruited were 1,178 glioma and 331 meningioma cases and 2,493 age- and gender-matched population controls. Only medical conditions occurring at least 2 years before brain tumour diagnosis were considered. Relative risks (RRs) and 95% confidence intervals (CIs) were estimated using a conditional logistic regression model. Heterogeneity between centres was tested. No association between meningioma and previous medical conditions was observed. For glioma, there was an increased risk associated with epilepsy (RR = 6.55, 95% CI 3.40-12.63), but this was considerably weaker for epilepsy of more than 20 years duration. The risk remained elevated after adjustment for use of anti-epileptic drugs. There was a statistically significant inverse association between glioma and all allergic diseases combined (RR = 0.59, 95% CI 0.49-0.71); this was also observed for specific allergic conditions, namely, asthma and eczema. Subjects who reported a history of infectious diseases (e.g., colds, flu) showed a 30% reduction in risk (RR = 0.72, 95% CI 0.61-0.85). The decreased risks for glioma in subjects reporting a history of allergic conditions or infectious diseases may indicate an influence of immunological factors on the development of glioma. The association between glioma and epilepsy has to be interpreted cautiously and needs further investigation.
DOI:doi:10.1002/(SICI)1097-0215(19990719)82:2<155¬AID-IJC1>3.0.CO;2-P
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Verlag: http://dx.doi.org/10.1002/(SICI)1097-0215(19990719)82:2<155AID-IJC1>3.0.CO;2-P
 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/%28SICI%291097-0215%2819990719%2982%3A2%3C155%3A%3AAID-IJC1%3E3.0.CO%3B2 ...
 DOI: https://doi.org/10.1002/(SICI)1097-0215(19990719)82:2<155AID-IJC1>3.0.CO;2-P
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1587437686
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68356901   QR-Code
zum Seitenanfang