Central corneal thickness in spectral-domain OCT and associations with ocular and systemic parameters

• Verfasst von: Schuster, Alexander K. [VerfasserIn]
• Verfasst von: Fischer, Joachim E. [VerfasserIn]
• Verfasst von: Voßmerbäumer, Urs [VerfasserIn]
• Titel: Central corneal thickness in spectral-domain OCT and associations with ocular and systemic parameters
• Verf.angabe: Alexander Karl-Georg Schuster, Joachim Ernst Fischer, and Urs Vossmerbaeumer
• Jahr: 2016
• Umfang: 6 S.
• Fussnoten: Gesehen am 19.02.2019
• Titel Quelle: Enthalten in: Journal of ophthalmology
• Ort Quelle: New York, NY : Hindawi, 2009
• Jahr Quelle: 2016
• Band/Heft Quelle: (2016), Artikel-ID 2596956, Seite 1-6
• ISSN Quelle: 2090-0058
• DOI: doi:10.1155/2016/2596956
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1587801701

Abstract

Background. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods. A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry, and imaging of the anterior segment by SD-OCT was performed. In parallel, a broad range of systemic cardiovascular parameters were measured. Associations were analyzed using a generalized estimating equations’ model. Results. CCT measurements showed a significant association with corneal curvature and intraocular pressure: a thinner CCT was associated with a flatter cornea and with lower intraocular pressure (). Age was positively associated with CCT (); all other cardiovascular parameters were not associated. Conclusion. A thinner cornea is associated with a flatter surface and with lower intraocular pressure readings, while there are no independent associations with refraction and systemic cardiovascular parameters. Our findings highlight the value of SD-OCT CCT measurements as a standard tool in anterior segment analysis.