Controllability and hippocampal activation during pain expectation in fibromyalgia syndrome

• Verfasst von: Gonzalez Roldan, Ana Maria [VerfasserIn]
• Verfasst von: Diesch, Eugen [VerfasserIn]
• Verfasst von: Flor, Herta [VerfasserIn]
• Titel: Controllability and hippocampal activation during pain expectation in fibromyalgia syndrome
• Verf.angabe: Ana María González-Roldán, Isabelle C. Bomba, Eugen Diesch, Pedro Montoya, Herta Flor, Sandra Kamping
• E-Jahr: 2016
• Jahr: December 2016
• Umfang: 10 S.
• Fussnoten: Gesehen am 05.03.2019 ; Available online 24 September 2016
• Titel Quelle: Enthalten in: Biological psychology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1973
• Jahr Quelle: 2016
• Band/Heft Quelle: 121(2016), Seite 39-48
• ISSN Quelle: 1873-6246
• DOI: doi:10.1016/j.biopsycho.2016.09.007
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Controllability
• Sach-SW: Expectation
• Sach-SW: Fibromyalgia
• Sach-SW: Imaging
• Sach-SW: Pain
• K10plus-PPN: 1588347680

Abstract

To examine the role of perceived control in pain perception, fibromyalgia patients and healthy controls participated in a reaction time experiment under different conditions of pain controllability. No significant differences between groups were found in pain intensity and unpleasantness ratings. However, during the expectation of uncontrollable pain, patients compared to controls showed higher hippocampal activation. In addition, hippocampal activity during the pain expectation period predicted activation of the posterior cingulate cortex (PCC), precuneus and hippocampus during pain stimulation in fibromyalgia patients. The increased activation of the hippocampus during pain expectation and subsequent activation of the PCC/precuneus during the lack of control phase points towards an influence of pain perception through heightening of alertness and anxiety responses to pain in fibromyalgia patients.