Mapping adolescent reward anticipation, receipt, and prediction error during the monetary incentive delay task

• Verfasst von: Cao, Zhipeng [VerfasserIn]
• Verfasst von: Banaschewski, Tobias [VerfasserIn]
• Verfasst von: Flor, Herta [VerfasserIn]
• Titel: Mapping adolescent reward anticipation, receipt, and prediction error during the monetary incentive delay task
• Verf.angabe: Zhipeng Cao, Marc Bennett, Catherine Orr, Ilknur Icke, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Uli Bromberg, Christian Büchel, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, Vincent Frouin, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Gunter Schumann, Robert Whelan, IMAGEN Consortium
• E-Jahr: 2019
• Jahr: January 2019
• Jahr des Originals: 2018
• Umfang: 22 S.
• Illustrationen: Illustrationen
• Fussnoten: First published: 21 September 2018 ; Gesehen am 28.03.2019
• Titel Quelle: Enthalten in: Human brain mapping
• Ort Quelle: New York, NY : Wiley-Liss, 1993
• Jahr Quelle: 2019
• Band/Heft Quelle: 40(2019), 1, Seite 262-283
• ISSN Quelle: 1097-0193
• DOI: doi:10.1002/hbm.24370
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: adolescence
• Sach-SW: functional connectivity
• Sach-SW: gender differences
• Sach-SW: reward processing
• Sach-SW: sensation seeking
• K10plus-PPN: 1662494416

Abstract

The functional neuroanatomy and connectivity of reward processing in adults are well documented, with relatively less research on adolescents, a notable gap given this developmental period's association with altered reward sensitivity. Here, a large sample (n = 1,510) of adolescents performed the monetary incentive delay (MID) task during functional magnetic resonance imaging. Probabilistic maps identified brain regions that were reliably responsive to reward anticipation and receipt, and to prediction errors derived from a computational model. Psychophysiological interactions analyses were used to examine functional connections throughout reward processing. Bilateral ventral striatum, pallidum, insula, thalamus, hippocampus, cingulate cortex, midbrain, motor area, and occipital areas were reliably activated during reward anticipation. Bilateral ventromedial prefrontal cortex and bilateral thalamus exhibited positive and negative activation, respectively, during reward receipt. Bilateral ventral striatum was reliably active following prediction errors. Previously, individual differences in the personality trait of sensation seeking were shown to be related to individual differences in sensitivity to reward outcome. Here, we found that sensation seeking scores were negatively correlated with right inferior frontal gyrus activity following reward prediction errors estimated using a computational model. Psychophysiological interactions demonstrated widespread cortical and subcortical connectivity during reward processing, including connectivity between reward-related regions with motor areas and the salience network. Males had more activation in left putamen, right precuneus, and middle temporal gyrus during reward anticipation. In summary, we found that, in adolescents, different reward processing stages during the MID task were robustly associated with distinctive patterns of activation and of connectivity.