Status: Bibliographieeintrag
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| Verfasst von: | Caroti, Francesca [VerfasserIn]  |
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| | Noeske, Viola [VerfasserIn] |
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| | Fath, Maike [VerfasserIn] |
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| | Schütz, Lucas [VerfasserIn] |
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| | Lemke, Steffen [VerfasserIn] |
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| Titel: | Decoupling from yolk sac is required for extraembryonic tissue spreading in the scuttle fly Megaselia abdita |
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| Verf.angabe: | Francesca Caroti, Everardo González Avalos, Viola Noeske, Paula González Avalos, Dimitri Kromm, Maike Wosch, Lucas Schütz, Lars Hufnagel, Steffen Lemke |
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| E-Jahr: | 2018 |
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| Jahr: | November 12, 2018 |
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| Umfang: | 19 S. |
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| Fussnoten: | Gesehen am 01.04.2019 ; Version of record published: November 12, 2018 (version 2) |
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| Titel Quelle: | Enthalten in: eLife |
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| Ort Quelle: | Cambridge : eLife Sciences Publications, 2012 |
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| Jahr Quelle: | 2018 |
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| Band/Heft Quelle: | 7(2018) Artikel-Nummer e34616 |
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| ISSN Quelle: | 2050-084X |
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| Abstract: | Extraembryonic tissues contribute to animal development, which often entails spreading over embryo or yolk. Apart from changes in cell shape, the requirements for this tissue spreading are not well understood. Here, we analyze spreading of the extraembryonic serosa in the scuttle fly Megaselia abdita. The serosa forms from a columnar blastoderm anlage, becomes a squamous epithelium, and eventually spreads over the embryo proper. We describe the dynamics of this process in long-term, whole-embryo time-lapse recordings, demonstrating that free serosa spreading is preceded by a prolonged pause in tissue expansion. Closer examination of this pause reveals mechanical coupling to the underlying yolk sac, which is later released. We find mechanical coupling prolonged and serosa spreading impaired after knockdown of M. abdita Matrix metalloprotease 1. We conclude that tissue-tissue interactions provide a critical functional element to constrain spreading epithelia. |
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| DOI: | doi:10.7554/eLife.34616 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.7554/eLife.34616 |
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| | DOI: https://doi.org/10.7554/eLife.34616 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | epithelial morphogenesis |
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| | EvoDevo |
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| | extraembryonic tissue |
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| | Megaselia abdita |
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| | serosa / amnion |
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| K10plus-PPN: | 1662580150 |
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| Verknüpfungen: | → Zeitschrift |
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Decoupling from yolk sac is required for extraembryonic tissue spreading in the scuttle fly Megaselia abdita / Caroti, Francesca [VerfasserIn]; November 12, 2018 (Online-Ressource)
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